{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:36:40Z","timestamp":1781739400828,"version":"3.54.5"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,6,20]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Life's Essential 8 (LE8) metrics for cardiovascular health (CVH) aid primordial prevention in US populations.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We conducted a child cohort study (PROC [Beijing Child Growth and Health Cohort]) with baseline (2018\u20132019) and follow\u2010up (2020\u20132021) assessments, enrolling disease\u2010free 6\u2010 to 10\u2010year\u2010old children from 6 elementary schools in Beijing. We collected LE8\u2010assessed components via questionnaire surveys and 3 cardiovascular structural parameters by 2\u2010dimensional M\u2010mode echocardiography: left ventricular mass (LVM), LVM index, and carotid intima\u2010media thickness. Compared with 1914 participants (mean age, 6.6\u2009years) at baseline, we saw lower mean CVH scores at follow\u2010up (n=1789; 8.5\u2009years). Among LE8 components, diet presented the lowest perfect\u2010score prevalence (5.1%). Only 18.6% of participants had physical activity \u2265420\u2009min\/wk, 55.9% had nicotine exposure, and 25.2% had abnormal sleep duration. Prevalence of overweight\/obesity was 26.8% at baseline and 38.2% at follow\u2010up. We noted optimal blood lipid scores in 30.7%, while 12.9% of children had abnormal fasting glucose. Normal BP was 71.6% at baseline and 60.3% at follow\u2010up. LVM (g), LVM index (g\/m\n              <jats:sup>2.7<\/jats:sup>\n              ), and carotid intima\u2010media thickness (mm) were significantly lower in children with high (56.8, 33.2, 0.35) or moderate CVH scores (60.6, 34.6, 0.36), compared with children with low CVH scores (67.9, 37.1, 0.37). Adjusting for age\/sex, LVM (\u03b2=11.8 [95% CI, 3.5\u201320.0];\n              <jats:italic>P<\/jats:italic>\n              =0.005), LVM index (\u03b2=4.4 [95% CI, 0.5\u20138.3];\n              <jats:italic>P<\/jats:italic>\n              =0.027), and carotid intima\u2010media thickness (\u03b2=0.016 [95% CI, 0.002\u20130.030];\n              <jats:italic>P<\/jats:italic>\n              =0.028) were higher in the low\u2010CVH group.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">CVH scores were suboptimal, declining with age. LE8 metrics indicated worse CVH in children with abnormal cardiovascular structural measurements, suggesting the validity of LE8 in assessing child CVH.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Registration<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.chictr.org.cn\/index.html\">https:\/\/www.chictr.org.cn\/index.html<\/jats:ext-link>\n              ; Unique identifier: ChiCTR2100044027.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.029077","type":"journal-article","created":{"date-parts":[[2023,6,11]],"date-time":"2023-06-11T02:28:20Z","timestamp":1686450500000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Validation of \u201cLife's Essential 8\u201d Metrics With Cardiovascular Structural Status in Children: The PROC Study in China"],"prefix":"10.1161","volume":"12","author":[{"given":"Wen","family":"Shu","sequence":"first","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"},{"name":"Peking Union Medical College, Chinese Academy of Medical Sciences Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menglong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huidi","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nubiya","family":"Amaerjiang","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5532-9100","authenticated-orcid":false,"given":"Nourhan M.","family":"Khattab","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawulan","family":"Zunong","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengying","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7289-8698","authenticated-orcid":false,"given":"Sten H.","family":"Vermund","sequence":"additional","affiliation":[{"name":"Yale School of Public Health Yale University New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4611-2206","authenticated-orcid":false,"given":"Yifei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Child, Adolescent Health and Maternal Care, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2022.100383"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2019.01.042"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1067072"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacasi.2021.09.007"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.109.192703"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000001078"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-021-01754-6"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu14061228"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.910291"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c00991"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2021.10.033"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-1904"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jev014"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90771-x"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)00540-7"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.10.002"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.0140"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.708044"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.118.10975"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2019.08.026"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12854"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-1536"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2022.07.011"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-6515-9"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.2147\/dmso.S319583"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.122.060911"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12937-022-00807-8"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/advances\/nmaa029"},{"key":"e_1_3_2_30_2","first-page":"1","article-title":"Status of meat consumption patterns of the residents aged 18\u201359 in 15 provinces (autonomous regions and municipalities) of China in 2015","volume":"48","author":"Wang Z","year":"2019","unstructured":"Wang Z, Zhang B, Wang H, Zhang Y, Su C, Zhang J, Jia X, Jiang H, Huang F, Ding G. Status of meat consumption patterns of the residents aged 18\u201359 in 15 provinces (autonomous regions and municipalities) of China in 2015. Wei Sheng Yan Jiu. 2019;48:1\u20138.","journal-title":"Wei Sheng Yan Jiu"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.3967\/bes2019.054"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/s2468-1253(17)30154-1"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1000-8020.1999.01.016"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu14112247"},{"key":"e_1_3_2_35_2","unstructured":"Healthy China Action Promotion Committee . Healthy China Initiative (2019\u20132030). Accessed November 1 2022. http:\/\/www.gov.cn\/xinwen\/2019\u201007\/15\/content_5409694.htm."},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.7.776"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz455"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0253-3758.2016.10.005"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001656"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2022.109884"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-3459"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-8587(21)00045-0"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.627741"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02397.x"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.122.029077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:45:50Z","timestamp":1715604350000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.122.029077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,20]]},"references-count":43,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,6,20]]}},"alternative-id":["10.1161\/JAHA.122.029077"],"URL":"https:\/\/doi.org\/10.1161\/jaha.122.029077","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,20]]},"assertion":[{"value":"2022-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e029077"}}