{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T08:16:32Z","timestamp":1788336992432,"version":"build-2803163510"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"14","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,7,18]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Despite the high burden of atrial fibrillation in cardiac amyloidosis (CA), the safety of catheter ablation therapy in CA is not well established. We sought to examine short\u2010term safety outcomes following atrial fibrillation ablation in patients with CA compared with matched patients with dilated cardiomyopathy (DCM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Using data from the National Inpatient Sample, we identified all hospitalizations for atrial fibrillation ablation from the fourth quarter of 2015 through 2019. Admissions for CA and DCM were matched in a 1:5 ratio using propensity scores based on the following sociodemographics: age, sex, race or ethnicity, payor, median income, comorbidities, and hospital characteristics. We compared in\u2010hospital outcomes between both cardiomyopathies. We identified 1395 unweighted hospitalizations (representing 6750 national hospitalizations) for atrial fibrillation ablation, out of which 45 (3.2%) were admissions for CA. Compared with DCM, patients with CA were older (72.9 versus 65.1\u2009years), had a higher burden of prior stroke (20.0% versus 8.6%) and chronic kidney disease (53.3% versus 33.6%), and were less likely to have a prior implantable cardioverter\u2010defibrillator (4.4% versus 23.0%). We successfully matched 42 CAs to 210 DCM hospitalizations. After matching, there was no difference in total complications (14.3% versus 10.5%,\n                      <jats:italic>P<\/jats:italic>\n                      =0.60), length\u2010of\u2010stay (3.1 versus 2.1\u2009days,\n                      <jats:italic>P<\/jats:italic>\n                      =0.23), home disposition (97.6% versus 96.2%,\n                      <jats:italic>P<\/jats:italic>\n                      =0.65), and total charges ($137\u2009250 versus $133\u2009910,\n                      <jats:italic>P<\/jats:italic>\n                      =0.24).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this nationally representative study of atrial fibrillation catheter ablation in CA, short\u2010term safety outcomes and complication rates were similar to a propensity score\u2010matched cohort of DCM. Further studies exploring long\u2010term safety outcomes are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.122.029339","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T07:00:03Z","timestamp":1689318003000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Safety of Catheter Ablation Therapy for Atrial Fibrillation in Cardiac Amyloidosis"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1663-1045","authenticated-orcid":false,"given":"Hassan A.","family":"Alhassan","sequence":"first","affiliation":[{"name":"Department of Medicine University of Pittsburgh Medical Center Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4758-4424","authenticated-orcid":false,"given":"Aleesha","family":"Kainat","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Pittsburgh Medical Center McKeesport PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6232-409X","authenticated-orcid":false,"given":"Joseph","family":"Donohue","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Pittsburgh Medical Center Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4745-4021","authenticated-orcid":false,"given":"Scott J.","family":"Baumgartner","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Pittsburgh Medical Center Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7123-2368","authenticated-orcid":false,"given":"Harriet","family":"Akunor","sequence":"additional","affiliation":[{"name":"Department of Medicine Albert Einstein College of Medicine\/Jacobi Medical Center Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4669-803X","authenticated-orcid":false,"given":"Samir","family":"Saba","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Jain","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1425-6536","authenticated-orcid":false,"given":"Prem","family":"Soman","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2021.06.006"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.121.318187"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2021.08.009"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.04.019"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.052136"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.12.024"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz314"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.63.6.1285"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13046"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13992"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.09.016"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.3109\/13506129.2015.1028616"},{"key":"e_1_3_1_14_2","unstructured":"HCUP\u2010US NIS overview . Agency for Healthcare Research and Quality. Accessed January 02 2022. \u00a0https:\/\/www.hcup\u2010us.ahrq.gov\/nisoverview.jsp"},{"key":"e_1_3_1_15_2","unstructured":"Elixhauser Comorbidity Software Refined for ICD\u201010\u2010CM . Agency for Healthcare Research and Quality. https:\/\/www.hcup\u2010us.ahrq.gov\/toolssoftware\/comorbidityicd10\/comorbidity_icd10.jsp"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.015721"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.0693"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.6004"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2580"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/03610910902859574"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxx063"},{"key":"e_1_3_1_22_2","unstructured":"HCUP\u2010US cost\u2010to\u2010charge ratio for inpatient files . Agency for Healthcare Research and Quality. 2022. https:\/\/hcup\u2010us.ahrq.gov\/db\/ccr\/ip\u2010ccr\/ip\u2010ccr.jsp"},{"key":"e_1_3_1_23_2","unstructured":"Houchens R Ross D Elixhauser A. Final report on calculating National Inpatient Sample (NIS) variances for data years 2012 and later. 2015. HCUP methods series report # 2015\u201009. Agency for Healthcare Research and Quality. Accessed June 29 2023. https:\/\/www.hcup\u2010us.ahrq.gov\/reports\/methods\/2015\u201009.pdf"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.17653"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1113566"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.467"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000768"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.057095"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1707855"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2021.07.010"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.10.079"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2020.01.002"},{"key":"e_1_3_1_33_2","unstructured":"HCUP quality control procedures . Agency for Healthcare Research and Quality. 2022. Accessed January 02 2022. https:\/\/www.hcup\u2010us.ahrq.gov\/db\/quality.jsp#procedures"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.122.029339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T08:24:27Z","timestamp":1715588667000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.122.029339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,18]]},"references-count":32,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2023,7,18]]}},"alternative-id":["10.1161\/JAHA.122.029339"],"URL":"https:\/\/doi.org\/10.1161\/jaha.122.029339","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,18]]},"assertion":[{"value":"2022-12-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e029339"}}