{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T04:52:54Z","timestamp":1788065574623,"version":"build-2784847793"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,7,4]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Data on the incidence, relevant patient factors, and clinical outcomes of the misdiagnosis of ST\u2010segment\u2013elevation myocardial infarction (STEMI) in the modern era of percutaneous coronary intervention are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Data from KAMIR (Korea Acute Myocardial Infarction Registry) between November 2011 and June 2020 were analyzed. Out of 28\u2009470 patients with acute myocardial infarction, 11\u2009796 were eventually diagnosed with STEMI following a coronary angiogram. They were classified into 2 groups: patients with an initial working diagnosis of STEMI before starting the initial treatment and patients with an initial working diagnosis of non\u2010STEMI (misdiagnosed group). Out of 11\u2009796 patients with a final diagnosis of STEMI, 165 (1.4%) were misdiagnosed. The door\u2010to\u2010angiography time in the misdiagnosed group was 5 times longer than that in the timely diagnosed group (median 220 [interquartile range {IQR}, 66\u20131177] versus 43 [IQR, 31\u201358] minutes;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). In a multivariable adjustments model, patients with a history of heart failure, atypical chest pain, anemia, or symptom\u2010to\u2010door time \u22654\u2009hours had significantly higher odds, whereas those with systolic blood pressure &lt;100\u2009mm\u2009Hg or anterior ST elevation or left bundle\u2010branch block on ECG had lower odds of STEMI misdiagnosis. For patients with culprit lesions in the left anterior descending artery (n=5838), the adjusted 1\u2010year mortality risk for STEMI misdiagnosis was 1.84 (95% CI, 1.01\u20133.38).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Misdiagnosis of STEMI is not rare and is associated with a significant delay in coronary angiography, resulting in increased 1\u2010year mortality for patients with culprit lesions in the left anterior descending artery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.123.029728","type":"journal-article","created":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T17:18:10Z","timestamp":1687454290000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Incidence, Relevant Patient Factors, and Clinical Outcomes of the Misdiagnosis of ST\u2010Segment\u2013Elevation Myocardial Infarction: Results From the Korea Acute Myocardial Infarction Registry"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0377-6352","authenticated-orcid":false,"given":"Kyung Hoon","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2217-5624","authenticated-orcid":false,"given":"Min\u2010Ho","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Chonnam National University Medical School Gwangju Hwasun\u2010gun South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6026-1702","authenticated-orcid":false,"given":"Min Chul","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4162-7902","authenticated-orcid":false,"given":"Doo Sun","family":"Sim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Joon","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju Han","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2022-9366","authenticated-orcid":false,"given":"Youngkeun","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-5329","authenticated-orcid":false,"given":"Hyo\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Seoul National University Medical School Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-1915","authenticated-orcid":false,"given":"Seung\u2010Ho","family":"Hur","sequence":"additional","affiliation":[{"name":"Department of Cardiology Keimyung University Dongsan Medical Center Daegu South 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Pusan National University Medical School Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7319-8562","authenticated-orcid":false,"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital and Medical School Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Korea Acute Myocardial Infarction Registry (KAMIR) 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