{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:55:14Z","timestamp":1793300114241,"version":"4.5.0"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,9,19]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Data on the use of the wearable cardioverter\u2010defibrillator (WCD) among patients with myocarditis remain sparse. Consequently, evidence for guideline recommendations in this patient population is lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      In total, 1596 consecutive patients were included in a multicenter registry from 8 European centers, with 124 patients (8%) having received the WCD due to myocarditis and reduced left ventricular ejection fraction or prior ventricular tachyarrhythmia. The mean age was 51.6\u00b116.3\u2009years, with 74% being male. Patients were discharged after index hospitalization on heart failure medication: Angiotensin\u2010converting enzyme inhibitors (62.5%), angiotensin\u2010receptor\u2010neprilysin inhibitor (22.9%), aldosterone\u2010antagonists (51%), or beta blockers (91.4%). The initial median left ventricular ejection fraction was 30% (22%\u201345%) and increased to 48% (39%\u201355%) over long\u2010term follow\u2010up (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). The median BNP (brain natriuretic peptide) level at baseline was 1702\u2009pg\/mL (565\u20133748) and decreased to 188\u2009pg\/mL (26\u2013348) over long\u2010term follow\u2010up (\n                      <jats:italic>P<\/jats:italic>\n                      =0.022). The mean wear time was 79.7\u00b152.1\u2009days and 21.0\u00b14.9\u2009hours per day. Arrhythmic event rates documented by the WCD were 9.7% for nonsustained ventricular tachycardia, 6.5% for sustained ventricular tachycardia, and 0% for ventricular fibrillation. Subsequently, 2.4% of patients experienced an appropriate WCD shock. The rate of inappropriate WCD shocks was 0.8%. All 3 patients with appropriate WCD shock had experienced ventricular tachycardia\/ventricular fibrillation before WCD prescription, with only 1 patient showing a left ventricular ejection fraction &lt;35%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients with myocarditis and risk for occurrence of ventricular tachyarrhythmia may benefit from WCD use. Prior ventricular arrhythmia might appear as a better risk predictor than a reduced left ventricular ejection fraction &lt;35% in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.123.030615","type":"journal-article","created":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T07:13:12Z","timestamp":1694157192000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Use of the Wearable Cardioverter\u2010Defibrillator Among Patients With Myocarditis and Reduced Ejection Fraction or Ventricular Tachyarrhythmia: Data From a Multicenter Registry"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0139-1045","authenticated-orcid":false,"given":"Ibrahim","family":"El\u2010Battrawy","sequence":"first","affiliation":[{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"},{"name":"Department of Molecular and Experimental Cardiology Institut f\u00fcr Forschung und Lehre (IFL), Ruhr University Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4516-6472","authenticated-orcid":false,"given":"Katharina","family":"Koepsel","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Tenbrink","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-5199","authenticated-orcid":false,"given":"Boldizsar","family":"Kovacs","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Heart Center, University Hospital Zurich Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0164-0838","authenticated-orcid":false,"given":"Tobias C.","family":"Dreher","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6962-9163","authenticated-orcid":false,"given":"Christian","family":"Blockhaus","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Centre Niederrhein, Helios Clinic Krefeld Krefeld Germany"},{"name":"Faculty of Health, School of Medicine University Witten\/Herdecke Witten Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5952-0284","authenticated-orcid":false,"given":"Michael","family":"Gotzmann","sequence":"additional","affiliation":[{"name":"Cardiology and Rhythmology University Hospital St. Josef\u2010Hospital Bochum, Ruhr University Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1358-1847","authenticated-orcid":false,"given":"Norbert","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Internal Intensive\u2010Care Medicine Klinikum St. Georg gGmbH Leipzig Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kuntz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Internal Intensive\u2010Care Medicine Klinikum St. Georg gGmbH Leipzig Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8804-933X","authenticated-orcid":false,"given":"Dong\u2010In","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Centre Niederrhein, Helios Clinic Krefeld Krefeld Germany"},{"name":"Faculty of Health, School of Medicine University Witten\/Herdecke Witten Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4524-3631","authenticated-orcid":false,"given":"Hendrik","family":"Lapp","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Heart Center Bonn University Hospital Bonn Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6106-8373","authenticated-orcid":false,"given":"Stephanie","family":"Rosenkaimer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4766-5523","authenticated-orcid":false,"given":"Mohammad","family":"Abumayyaleh","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University Mannheim Germany"},{"name":"German Center for Cardiovascular Research (DZHK) Partner Site Heidelberg\u2010Mannheim Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3053-0008","authenticated-orcid":false,"given":"Nazha","family":"Hamdani","sequence":"additional","affiliation":[{"name":"Department of Molecular and Experimental Cardiology Institut f\u00fcr Forschung und Lehre (IFL), Ruhr University Bochum Bochum 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