{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:19:02Z","timestamp":1783117142722,"version":"3.54.6"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,3,19]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Long\u2010term survival after single\u2010ventricle palliation and the effect of dominant ventricle morphology in large, unselected series of patients are scarcely reported.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">This nationwide cohort study included all children undergoing operation with single\u2010ventricle palliation during their first year of life in Sweden between January 1994 and December 2019. Data were obtained from institutional records and assessment of underlying cardiac anomaly and dominant ventricular morphology was based on complete review of medical records, surgical reports, and echocardiographic examinations. Data on vital status and date of death were retrieved from the Swedish Cause of Death Register, allowing for complete data on survival. Among 766 included patients, 333 patients (43.5%) were classified as having left or biventricular dominance, and 432 patients (56.4%) as having right ventricular (RV) dominance (of whom 231 patients had hypoplastic left heart syndrome). Follow\u2010up was 98.7% complete (10 patients emigrated). Mean follow\u2010up was 11.3\u2009years (maximum, 26.7\u2009years). Long\u2010term survival was significantly higher in patients with left ventricular compared with RV dominance (10\u2010year survival: 91.0% [95% CI, 87.3%\u201393.6%] versus 71.1% [95% CI, 66.4%\u201375.2%]). RV dominance had a significant impact on outcomes after first\u2010stage palliation but was also associated with impaired survival after completed total cavopulmonary connection. In total, 34 (4.4%) patients underwent heart transplantation. Of these 34 patients, 25 (73.5%) had predominant RV morphology.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">This study provides clinically relevant knowledge about the long\u2010term prognosis in patients with different underlying cardiac anomalies undergoing single\u2010ventricle palliation. RV dominance had a significant impact on outcomes after initial surgical treatment but was also associated with impaired survival after completed Fontan circulation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Registration<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              ; Unique identifier: NCT03356574.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.123.031722","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T11:01:17Z","timestamp":1710759677000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Long\u2010Term Survival After Single\u2010Ventricle Palliation: A Swedish 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