{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T00:10:01Z","timestamp":1786666201955,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,3,19]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Reports of intravascular thrombosis and cardiac complications have raised concerns about the safety of COVID\u201019 vaccinations, particularly in patients with high cardiovascular risk. Herein, we aimed to analyze the impact of preoperative COVID\u201019 vaccination on outcomes after coronary artery bypass grafting (CABG).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Among 520 patients who underwent isolated CABG from 2020 to 2022, 481 patients (mean\u00b1SD age: 67\u00b111\u2009years, 86 women) whose COVID\u201019 vaccination status could be confirmed were included. A total of 249 patients who had not received any COVID\u201019 vaccine before CABG (never vaccinated group) and 214 patients who had completed primary vaccination (fully vaccinated group) were subjected to 1:1 propensity score matching, and 156 pairs of patients were matched. There was no significant difference in early mortality between the 2 groups after matching. After matching, overall survival (\n              <jats:italic>P<\/jats:italic>\n              =0.930) and major adverse cardiovascular and cerebrovascular event\u2010free survival (\n              <jats:italic>P<\/jats:italic>\n              =0.636) did not differ between the 2 groups. One\u2010year graft patency also did not differ significantly between the 2 groups; all patent grafts in 85\/104 patients (82%) and 62\/73 patients (85%) in the never vaccinated and fully vaccinated groups, respectively (\n              <jats:italic>P<\/jats:italic>\n              =0.685). Subgroup analysis showed equivalent overall and major adverse cardiovascular and cerebrovascular event\u2010free survival among AstraZeneca and Pfizer vaccine recipients and between those with \u226430\u2009days versus &gt;30\u2009days from vaccination to CABG.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Despite the very high cardiovascular risk for patients undergoing CABG, COVID\u201019 vaccination did not affect major outcomes after CABG. Therefore, there is no reason for patients with coronary artery disease requiring CABG to avoid preoperative COVID\u201019 vaccination.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.123.032426","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T02:10:02Z","timestamp":1710295802000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Influence of Preoperative COVID\u201019 Vaccination on Outcomes After Coronary Artery Bypass Grafting\u2014A Propensity Score\u2013Matched Analysis"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5516-0333","authenticated-orcid":false,"given":"Hyoung Woo","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soyeon","family":"Ahn","sequence":"additional","affiliation":[{"name":"Biostatistics, Medical Research Collaborating Center Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4285-8200","authenticated-orcid":false,"given":"Jun Sung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6589-1519","authenticated-orcid":false,"given":"Hyun Jeong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You Kyeong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8392-6014","authenticated-orcid":false,"given":"Kang Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8313-8053","authenticated-orcid":false,"given":"Sang Yoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Chungnam National University Hospital Daejeon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4555-5782","authenticated-orcid":false,"given":"Joon Chul","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4769-5340","authenticated-orcid":false,"given":"Jae Hang","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0913-7014","authenticated-orcid":false,"given":"Cheong","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1111-9627","authenticated-orcid":false,"given":"Kay\u2010Hyun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Seoul National University Bundang Hospital Seongnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2022.09.053"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.16883"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.6515\/ACS.202211_38(6).20220508B"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.5872"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jscai.2022.100551"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.6431"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.25536"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.16887"},{"key":"e_1_3_1_10_2","unstructured":"Korea Disease Control and Prevention Agency . Update in COVID\u201019 domestic incidence and vaccination status. 2021. Accessed November 1 2021. https:\/\/www.kdca.go.kr\/board\/board.es?mid=a20501010000&bid=0015&list_no=717406&cg_code=&act=view&nPage=67"},{"key":"e_1_3_1_11_2","volume-title":"Guidance for Clinical Case Management of Thrombosis with Thrombocytopenia Syndrome (TTS) Following Vaccination to Prevent Coronavirus Disease (COVID\u201019): Interim Guidance","author":"World Health Organization","year":"2021","unstructured":"World Health Organization . Guidance for Clinical Case Management of Thrombosis with Thrombocytopenia Syndrome (TTS) Following Vaccination to Prevent Coronavirus Disease (COVID\u201019): Interim Guidance. World Health Organization; 2021. Accessed November 1, 2021. https:\/\/www.who.int\/publications\/i\/item\/9789240061989"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe2106315"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.7517"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-021-01712-8"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12959-021-00318-2"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.056135"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26132"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2021.06.047"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.2217\/fca.11.63"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n699"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.123.032426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:21:53Z","timestamp":1715602913000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.123.032426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,19]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,3,19]]}},"alternative-id":["10.1161\/JAHA.123.032426"],"URL":"https:\/\/doi.org\/10.1161\/jaha.123.032426","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,19]]},"assertion":[{"value":"2023-11-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e032426"}}