{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:05:36Z","timestamp":1790233536783,"version":"4.1.0"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,5,7]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Hypertension is a stroke risk factor with known disparities in prevalence and management between Black and White patients. We sought to identify if racial differences in presenting blood pressure (BP) during acute ischemic stroke exist.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Adults with acute ischemic stroke presenting to an emergency department within 24\u2009hours of last known normal during study epochs 2005, 2010, and 2015 within the Greater Cincinnati\/Northern Kentucky Stroke Study were included. Demographics, histories, arrival BP, National Institutes of Health Stroke Scale score, and time from last known normal were collected. Multivariable linear regression was used to determine differences in mean BP between Black and White patients, adjusting for age, sex, National Institutes of Health Stroke Scale score, history of hypertension, hyperlipidemia, smoking, stroke, body mass index, and study epoch. Of 4048 patients, 853 Black and 3195 White patients were included. In adjusted analysis, Black patients had higher presenting systolic BP (161\u2009mm\u2009Hg [95% CI, 159\u2013164] versus 158\u2009mm\u2009Hg [95% CI, 157\u2013159],\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01), diastolic BP (86\u2009mm\u2009Hg [95% CI, 85\u201388] versus 83\u2009mm\u2009Hg [95% CI, 82\u201384],\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01), and mean arterial pressure (111\u2009mm\u2009Hg [95% CI, 110\u2013113] versus 108\u2009mm\u2009Hg [95% CI, 107\u2013109],\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01) compared with White patients. In adjusted subanalysis of patients &lt;4.5\u2009hours from last known normal, diastolic BP (88\u2009mm\u2009Hg [95% CI, 86\u201390] versus 83\u2009mm\u2009Hg [95% CI, 82\u201384],\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01) and mean arterial pressure (112\u2009mm\u2009Hg [95% CI, 110\u2013114] versus 108\u2009mm\u2009Hg [95% CI, 107\u2013109],\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01) were also higher in Black patients.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">This population\u2010based study suggests differences in presenting BP between Black and White patients during acute ischemic stroke. Further study is needed to determine whether these differences influence clinical decision\u2010making, outcome, or clinical trial eligibility.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.123.032645","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T10:22:55Z","timestamp":1714731775000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A\u00a0Population Study"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3515-4005","authenticated-orcid":false,"given":"Yasmin N.","family":"Aziz","sequence":"first","affiliation":[{"name":"Department of Neurology and Rehabilitation Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3933-1574","authenticated-orcid":false,"given":"Heidi","family":"Sucharew","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3804-5063","authenticated-orcid":false,"given":"Robert J.","family":"Stanton","sequence":"additional","affiliation":[{"name":"Department of Neurology and Rehabilitation Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1620-4721","authenticated-orcid":false,"given":"Kathleen","family":"Alwell","sequence":"additional","affiliation":[{"name":"Department of Neurology and Rehabilitation Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6534-3029","authenticated-orcid":false,"given":"Simona","family":"Ferioli","sequence":"additional","affiliation":[{"name":"Department of Neurology and Rehabilitation Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7344-8266","authenticated-orcid":false,"given":"Pooja","family":"Khatri","sequence":"additional","affiliation":[{"name":"Department of Neurology and Rehabilitation Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8666-5369","authenticated-orcid":false,"given":"Opeolu","family":"Adeoye","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Washington University St Louis MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6247-010X","authenticated-orcid":false,"given":"Matthew L.","family":"Flaherty","sequence":"additional","affiliation":[{"name":"Department of Neurology and Rehabilitation Medicine University of Cincinnati Cincinnati OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6867-8630","authenticated-orcid":false,"given":"Jason","family":"Mackey","sequence":"additional","affiliation":[{"name":"Department of Neurology Indiana University Indianapolis IN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4465-9280","authenticated-orcid":false,"given":"Felipe","family":"De Los Rios La Rosa","sequence":"additional","affiliation":[{"name":"Baptist Health South Florida Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0850-9691","authenticated-orcid":false,"given":"Sharyl R.","family":"Martini","sequence":"additional","affiliation":[{"name":"Department of Neurology Michael E. 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