{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:59:43Z","timestamp":1780379983974,"version":"3.54.1"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,4,2]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Dialysis is a rare but serious complication after transcatheter aortic valve replacement. We analyzed the large multicenter TRITAVI (transfusion requirements in transcatheter aortic valve implantation) registry in order to develop and validate a clinical score assessing this risk.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              A total of 10\u2009071 consecutive patients were enrolled in 19 European centers. Patients were randomly assigned (2:1) to a derivation and validation cohort. Two scores were developed, 1 including only preprocedural variables (TRITAVIpre) and 1 also including procedural variables (TRITAVIpost). In the 6714 patients of the derivation cohort (age 82\u00b16\u2009years, 48% men), preprocedural factors independently associated with dialysis and included in the TRITAVIpre score were male sex, diabetes, prior coronary artery bypass graft, anemia, nonfemoral access, and creatinine clearance &lt;30\u2009mL\/min per m\n              <jats:sup>2<\/jats:sup>\n              . Additional independent predictors among procedural features were volume of contrast, need for transfusion, and major vascular complications. Both scores showed a good discrimination power for identifying risk for dialysis with C\u2010statistic 0.78 for TRITAVIpre and C\u2010statistic 0.88 for TRITAVIpost score. Need for dialysis increased from the lowest to the highest of 3 risk score groups (from 0.3% to 3.9% for TRITAVIpre score and from 0.1% to 6.2% for TRITAVIpost score). Analysis of the 3357 patients of the validation cohort (age 82\u00b17\u2009years, 48% men) confirmed the good discrimination power of both scores (C\u2010statistic 0.80 for TRITAVIpre and 0.81 for TRITAVIpost score). Need for dialysis was associated with a significant increase in 1\u2010year mortality (from 6.9% to 54.4%;\n              <jats:italic>P<\/jats:italic>\n              =0.0001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">A simple preprocedural clinical score can help predict the risk of dialysis after transcatheter aortic valve replacement.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.123.032955","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T11:56:40Z","timestamp":1711540600000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Risk Score for Prediction of Dialysis After Transcatheter Aortic Valve Replacement"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7409-5792","authenticated-orcid":false,"given":"Vincenzo","family":"Pasceri","sequence":"first","affiliation":[{"name":"San Filippo Neri Hospital Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Pelliccia","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences University Sapienza Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5546-262X","authenticated-orcid":false,"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7502-8049","authenticated-orcid":false,"given":"George","family":"Dangas","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New 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Hospital, University of Helsinki Lappeenranta Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6646-9317","authenticated-orcid":false,"given":"Fabrizio","family":"D'Ascenzo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Citt\u00e0 della Salute e della Scienza Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9969-2649","authenticated-orcid":false,"given":"Francesco","family":"Saia","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Vascular Surgery University Hospital Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3881-168X","authenticated-orcid":false,"given":"Giampaolo","family":"Luzi","sequence":"additional","affiliation":[{"name":"Cardiovascular Department Azienda Ospedaliera Regionale \u201cSan Carlo\u201d Potenza 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