{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:23:12Z","timestamp":1790198592189,"version":"4.1.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,3,5]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The ECG is a simple, noninvasive screening method for cardiovascular disease and arrhythmia. The impact of ECG abnormality on mortality is not certain in low\u2010risk populations. To address this, we evaluated the association between ECG abnormality and mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We retrospectively assessed baseline ECG and all\u2010cause mortality and cardiovascular mortality in 660\u2009383 patients presenting for medical check\u2010ups. Baseline ECG abnormalities were classified according to the Minnesota Code. Among the total 660\u2009383 participants, 23\u2009609 (3.6%) had major and 110\u2009038 (16.7%) had minor ECG abnormalities. All\u2010cause mortality occurred in 7751 patients (1.1%) and cardiovascular mortality in 1180 (0.18%) over a median follow\u2010up period of 8.8\u2009years. Major ECG abnormalities were associated with all\u2010cause mortality (hazard ratio [HR], 1.11 [95%, 1.03\u20131.2]) and cardiovascular mortality (HR, 1.92 [95% CI, 1.63\u20132.27]) compared with no ECG abnormalities. All\u2010cause mortality was associated with right atrial enlargement (HR, 2.11 [95% CI, 1.1\u20134.07]), left atrial enlargement (HR, 1.76 [95% CI, 1.1\u20132.84]), sinus tachycardia (HR, 1.52 [95% CI, 1.15\u20132.01]), complete atrioventricular block (HR, 2.1 [95% CI, 1.05\u20134.2]), atrial fibrillation (HR, 1.52 [95% CI, 1.26\u20131.84]), and left ventricular hypertrophy (HR, 1.15 [95% CI, 1.02\u20131.3]). Cardiovascular mortality was associated with left atrial enlargement (HR, 4.52 [95% CI, 2.15\u20139.5]), atrial fibrillation (HR, 3.22 [95% CI, 2.33\u20134.46]), left ventricular hypertrophy (HR, 1.72 [95% CI, 1.35\u20132.19]), major Q\u2010wave abnormality (HR, 1.6 [95% CI, 1.08\u20132.39]), and major ST\u2010T abnormality (HR, 1.76 [95% CI, 1.01\u20133.04]).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">ECG abnormalities, including left atrial enlargement, left ventricular hypertrophy, atrial fibrillation, and major Q\u2010wave and ST\u2010T abnormalities, were associated with cardiovascular mortality in a low\u2010risk population.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.123.033306","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T10:21:14Z","timestamp":1709202074000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":22,"title":["Association Between ECG Abnormalities and Mortality in a Low\u2010Risk Population"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1018-7871","authenticated-orcid":false,"given":"Sung Ho","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2119-9226","authenticated-orcid":false,"given":"Mi Yeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Biostatistics, Department of R&amp;D Management, 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