{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T09:02:18Z","timestamp":1790326938665,"version":"4.1.0"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,5,21]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Evidence regarding sex differences in the associations of traditional risk factors with incident heart failure (HF) hospitalization among Chinese general adults is insufficient. This study aimed to evaluate the potential sex differences in the associations of traditional risk factors with HF among Chinese general adults.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Data were from a subcohort of the China PEACE (Patient\u2010Centered Evaluative Assessment of Cardiac Events) Million Persons Project. The traditional risk factors were collected at baseline, and the study outcome was HF\u2010related hospitalization identified from the Inpatients Registry.<\/jats:p>\n            <jats:p xml:lang=\"en\">\n              A total of 102\u2009278 participants (mean age, 54.3\u2009years; 39.5% men) without prevalent HF were recruited. A total of 1588 cases of HF\u2010related hospitalization were captured after a median follow\u2010up of 3.52\u2009years. The incidence rates were significantly higher in men (2.1%) than in women (1.2%). However, the observed lower risk of HF in women was significantly attenuated or even vanished when several traditional risk factors were poorly controlled (\n              <jats:italic>P<\/jats:italic>\n              for sex\u2010by\u2010risk factors &lt;0.05). The selected 11 risk factors collectively explained 62.5% (95% CI, 55.1\u201368.8) of population attributable fraction for HF in women, which is much higher than in men (population attributable fraction, 39.6% [95% CI, 28.5\u201348.9]).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Although women had a lower incidence rate of hospitalization for HF than men in this study, the risk for HF increased more remarkably in women than in men when several traditional risk factors were poorly controlled. This study suggests that intensive preventative strategies are immediately needed in China.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.123.033777","type":"journal-article","created":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T10:33:12Z","timestamp":1715337192000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Sex Differences in the Associations of Traditional Risk Factors and Incident Heart Failure Hospitalization: A Prospective Cohort Study of 102\u2009278 Chinese General Adults"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2206-8439","authenticated-orcid":false,"given":"Weida","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Cardiology, Hypertension Research Laboratory Guangdong Cardiovascular Institute, Guangdong Provincial People\u2019s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University Guangzhou 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