{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:00:46Z","timestamp":1780524046092,"version":"3.54.1"},"reference-count":47,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Type A aortic dissection presents challenges with postoperative cerebral complications, and this study evaluates the predictive value of quantitative electroencephalography for perioperative brain function prognosis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Amplitude\u2010integrated electroencephalography (aEEG) processes raw signals through filtering, amplitude integration, and time compression, displaying the data in a semilogarithmic format. Using this method, postoperative relative band power (post\u2010RBP) \u03b1% and dynamic aEEG (\u0394aEEG) grade were significantly associated with neurological dysfunction in univariate and multivariable analyses, with area under the receiver operating characteristic curve of 0.876 (95% CI, 0.825\u20130.926) for the combined model. Postoperative relative band power \u03b1% and \u0394aEEG were significantly associated with adverse outcomes, with area under the receiver operating characteristic curve of 0.903 (95% CI, 0.835\u20130.971) for the combined model. Postoperative relative band power \u03b1% and \u0394aEEG were significantly associated with transient neurological dysfunction and stroke, with areas under the receiver operating characteristic curve of 0.818 (95% CI, 0.760\u20130.876) and 0.868 (95% CI, 0.810\u20130.926) for transient neurological dysfunction, and 0.815 (95% CI, 0.743\u20130.886) and 0.831 (95% CI, 0.746\u20130.916) for stroke. Among 56 patients, the Alberta Stroke Program Early Computed Tomography score was superior to \u0394aEEG in predicting neurological outcomes (area under the receiver operating characteristic curve of 0.872 versus 0.708 [95% CI, 0.633\u20130.783];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Perioperative quantitative electroencephalography monitoring offers valuable insights into brain function changes in patients with type A aortic dissection. \u2206aEEG grades can aid in early detection of adverse outcomes, while postoperative relative band power and \u2206aEEG grades predict transient neurological dysfunction. Quantitative electroencephalography can assist cardiac surgeons in assessing brain function and improving outcomes in patients with type A aortic dissection.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Registration<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.chictr.org.cn\">https:\/\/www.chictr.org.cn<\/jats:ext-link>\n              ; Unique identifier: ChiCTR2200055980.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.034351","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T09:34:19Z","timestamp":1726652059000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Quantitative Electroencephalography for Predication of Neurological Dysfunction in Type A Aortic Dissection: A Prospective Observational Study"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8594-7425","authenticated-orcid":false,"given":"Ya\u2010peng","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences &amp; 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