{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:01:26Z","timestamp":1790312486988,"version":"4.1.0"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,6,18]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Acute mesenteric ischemia is rare, and few large\u2010scale trials have evaluated endovascular therapy (EVT) and open surgical revascularization (OS). This study aimed to assess clinical outcomes after EVT or OS for acute superior mesenteric artery occlusion and identify predictors of mortality and bowel resection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Data from the Japanese Registry of All Cardiac and Vascular Diseases\u2010Diagnosis Procedure Combination (JROAD\u2010DPC) database from April 2012 to March 2020 were retrospectively analyzed. Overall, 746 patients with acute superior mesenteric artery occlusion who underwent revascularization were classified into 2 groups: EVT (n=475) or OS (n=271). The primary clinical outcome was in\u2010hospital mortality. The secondary outcomes were bowel resection, bleeding complications (transfusion or endoscopic hemostasis), major adverse cardiovascular events, hospitalization duration, and cost. The in\u2010hospital death or bowel resection rate was \u224830%. In\u2010hospital mortality (22.5% versus 21.4%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.72), bowel resection (8.2% versus 8.5%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.90), and major adverse cardiovascular events (11.6% versus 9.2%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.32) were comparable between the EVT and OS groups. Hospitalization duration in the EVT group was 6\u2009days shorter than that in the OS group, and total hospitalization cost was 0.88\u2009million yen lower. Interaction analyses revealed that EVT and OS had no significant difference in terms of in\u2010hospital death in patients with thromboembolic and atherothrombotic characteristics. Advanced age, decreased activities of daily living, chronic kidney disease, and old\u00a0myocardial infarction were significant predictive factors for in\u2010hospital mortality. Diabetes was a predictor of bowel resection after revascularization.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">EVT was comparable to OS in terms of clinical outcomes in patients with acute superior mesenteric artery occlusion. Some predictive factors for mortality or bowel resection were obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.umin.ac.jp\/ctr\/\">www.umin.ac.jp\/ctr\/<\/jats:ext-link>\n                      ; Unique Identifier: UMIN000045240.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.035017","type":"journal-article","created":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T22:52:36Z","timestamp":1718491956000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Comparison of Endovascular Therapy and Open Surgical Revascularization in Patients With Acute Superior Mesenteric Artery Occlusion: A Large\u2010Scale Analysis Based on the JROAD\u2010DPC Database"],"prefix":"10.1161","volume":"13","author":[{"given":"Daiki","family":"Goto","sequence":"first","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6158-9395","authenticated-orcid":false,"given":"Kenji","family":"Yanishi","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7658-1163","authenticated-orcid":false,"given":"Takaaki","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5404-7432","authenticated-orcid":false,"given":"Hirofumi","family":"Kawamata","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2453-3372","authenticated-orcid":false,"given":"Ayumu","family":"Fujioka","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3387-9774","authenticated-orcid":false,"given":"Tomotsugu","family":"Seki","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kan","family":"Zen","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9373-4331","authenticated-orcid":false,"given":"Satoaki","family":"Matoba","sequence":"additional","affiliation":[{"name":"Kyoto Prefectural University of Medicine","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.03.004"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.05.084"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.09.049"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.06.084"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2017.01.010"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01613.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000154269.52294.57"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-015-2830-3"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4459"},{"key":"e_1_3_2_11_2","first-page":"489","article-title":"Acute mesenteric ischemia","volume":"114","author":"Stoney RJ","year":"1993","unstructured":"Stoney RJ, Cunningham CG. Acute mesenteric ischemia. Surgery. 1993;114:489\u2013490.","journal-title":"Surgery"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.833464"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.01.067"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/2047487320904641"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-79700-5"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-20-0655"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002592"},{"key":"e_1_3_2_18_2","first-page":"61","article-title":"Functional evaluation: the Barthel index","volume":"14","author":"Mahoney FI","year":"1965","unstructured":"Mahoney FI, Barthel DW. Functional evaluation: the Barthel index. Maryland State Med J. 1965;14:61\u201365.","journal-title":"Maryland State Med J"},{"key":"e_1_3_2_19_2","first-page":"684","article-title":"The effect of bronchitis, smoking, and occupation on ventilation","volume":"87","author":"Brinkman GL","year":"1963","unstructured":"Brinkman GL, Coates EO Jr. The effect of bronchitis, smoking, and occupation on ventilation. Am Rev Respir Dis. 1963;87:684\u2013693.","journal-title":"Am Rev Respir Dis"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.118593"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1053\/bega.2000.0157"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.12.017"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.04.045"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.120373"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.06.204"},{"key":"e_1_3_2_26_2","first-page":"351","article-title":"Embolectomy in mesenteric ischemia","volume":"83","author":"Lobo Mart\u00ednez E","year":"1993","unstructured":"Lobo Mart\u00ednez E, Mero\u00f1o Carvajosa E, Sacco O, Mart\u00ednez ME. Embolectomy in mesenteric ischemia. Rev Esp Enferm Dig. 1993;83:351\u2013354.","journal-title":"Rev Esp Enferm Dig"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1080\/110241500447263"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2002.02150.x"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-009-0828-4"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1964765"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1186\/1749-7922-4-41"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2012.07.022"},{"key":"e_1_3_2_33_2","first-page":"561","article-title":"New concepts in the management of emboli of the superior mesenteric artery","volume":"153","author":"Boley SJ","year":"1981","unstructured":"Boley SJ, Feinstein FR, Sammartano R, Brandt LJ, Sprayregen S. New concepts in the management of emboli of the superior mesenteric artery. Surg Gynecol Obstet. 1981;153:561\u2013569.","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_3_2_34_2","first-page":"123","article-title":"Acute mesenteric ischaemia","volume":"158","author":"Inderbitzi R","year":"1992","unstructured":"Inderbitzi R, Wagner HE, Seiler C, Stirnemann P, Gertsch P. Acute mesenteric ischaemia. Eur J Surg. 1992;158:123\u2013126.","journal-title":"Eur J Surg"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.02.011"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2011.09.015"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-008-9392-8"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2291020991"},{"key":"e_1_3_2_39_2","first-page":"139","article-title":"Multidetector CT angiography in the evaluation of acute mesenteric ischemia","volume":"20","author":"Ofer A","year":"2013","unstructured":"Ofer A, Abadi S, Nitecki S, Karram T, Kogan I, Leiderman M, Shmulevsky P, Israelit S, Engel A. Multidetector CT angiography in the evaluation of acute mesenteric ischemia. Emerg Radiol. 2013;20:139\u2013147.","journal-title":"Emerg Radiol"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2010.07.016"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10091938"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2010.01.017"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9330"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.124.035017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:56:03Z","timestamp":1790312163000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.124.035017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,18]]},"references-count":42,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,6,18]]}},"alternative-id":["10.1161\/JAHA.124.035017"],"URL":"https:\/\/doi.org\/10.1161\/jaha.124.035017","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,18]]},"assertion":[{"value":"2024-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e035017"}}