{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T08:38:34Z","timestamp":1769589514204,"version":"3.49.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Limited research has explored balance problems as a prospective risk factor for cardiovascular disease (CVD). This study aimed to characterize the association between balance measures and the risk of incident CVD in a population of 70\u2010year\u2010olds.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              From 2012 to 2022 a cohort of 4927 older individuals who were CVD free underwent balance assessments using a balance board. Measurements included lateral and anterior\u2013posterior sway, along with a safety limit of stability in a subcohort (N=2782). Time to first hospitalization for CVD, encompassing stroke, myocardial infarction, or angina pectoris was the primary outcome. Multivariable regression models assessed associations between balance parameters and CVD risk. Over a mean follow\u2010up of 4.9\u2009years, 320 individuals were hospitalized for CVD. In a balance test with eyes open, increased lateral sway at baseline was associated with a higher risk of CVD (hazard ratio [HR], 1.014 [95% CI, 1.004\u20131.025],\n              <jats:italic>P<\/jats:italic>\n              =0.005, per mm increased sway), after adjustment for traditional risk factors for CVD. Similarly, individuals with CVD during follow\u2010up exhibited higher lateral sway with eyes closed at baseline (HR, 1.015 [95% CI, 1.005\u20131.025],\n              <jats:italic>P<\/jats:italic>\n              =0.002, per mm increased sway), after multivariable adjustment. The 4 strongest independent predictors of CVD included lateral sway and were associated with a population attributable fraction of 61% (95% CI, 54\u201368).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">In community\u2010dwelling 70\u2010year\u2010olds, impaired lateral balance was an independent predictor of later CVD, after adjustment for traditional risk factors. This may suggest that position balance could be used as an early risk marker for underlying atherosclerotic disease.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.035073","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T09:27:33Z","timestamp":1726651653000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Impaired Balance Predicts Cardiovascular Disease in 70\u2010Year\u2010Old Individuals\u2014An Observational Study From the Healthy Aging Initiative"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3534-456X","authenticated-orcid":false,"given":"Anna","family":"Nordstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Rehabilitation Medicine Uppsala University, Uppsala University Hospital Uppsala Sweden"},{"name":"School of Sport Sciences UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2924-508X","authenticated-orcid":false,"given":"Peter","family":"Nordstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Public Health and Caring Sciences, Clinical Geriatrics Uppsala University, Uppsala University Hospital Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31012-1"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/1747493016676285"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00767.2019"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glaa097"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2019.01.008"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afl084"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2020.111038"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2008.05.008"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2006.00762.x"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-008-0749-7"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.66"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2017.05.014"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.3757\/jser.79.57"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03325221"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003135"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afx083"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-11-450"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206916"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000089820"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.28030"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2003.05.012"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/10749357.2021.1943803"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.124.035073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T09:44:13Z","timestamp":1728467053000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.124.035073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":22,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1161\/JAHA.124.035073"],"URL":"https:\/\/doi.org\/10.1161\/jaha.124.035073","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e035073"}}