{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:07:19Z","timestamp":1790705239653,"version":"4.1.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,7,2]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The study aimed to describe the patterns and trends of initiation, discontinuation, and adherence of oral anticoagulation (OAC) in patients with new\u2010onset postoperative atrial fibrillation (POAF), and compare with patients newly diagnosed with non\u2010POAF.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              This retrospective cohort study identified patients newly diagnosed with atrial fibrillation or flutter between 2012 and 2021 using administrative claims data from OptumLabs Data Warehouse. The POAF cohort included 118\u2009366 patients newly diagnosed with atrial fibrillation or flutter within 30\u2009days after surgery. The non\u2010POAF cohort included the remaining 315\u2009832 patients who were newly diagnosed with atrial fibrillation or flutter but not within 30\u2009days after a surgery. OAC initiation increased from 28.9% to 44.0% from 2012 to 2021 in POAF, and 37.8% to 59.9% in non\u2010POAF; 12\u2010month medication adherence increased from 47.0% to 61.8% in POAF, and 59.7% to 70.4% in non\u2010POAF. The median time to OAC discontinuation was 177\u2009days for POAF, and 242\u2009days for non\u2010POAF. Patients who saw a cardiologist within 90\u2009days of the first atrial fibrillation or flutter diagnosis, regardless of POAF or non\u2010POAF, were more likely to initiate OAC (odds ratio, 2.92 [95% CI, 2.87\u20132.98];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001), adhere to OAC (odds ratio, 1.08 [95% CI, 1.04\u20131.13];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001), and less likely to discontinue (odds ratio, 0.83 [95% CI, 0.82\u20130.85];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001) than patients who saw a surgeon or other specialties.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">The use of and adherence to OAC were higher in non\u2010POAF patients than in POAF patients, but they increased over time in both groups. Patients managed by cardiologists were more likely to use and adhere to OAC, regardless of POAF or non\u2010POAF.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.035708","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T15:02:04Z","timestamp":1719500524000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Ten\u2010Year Trend of Oral Anticoagulation Use in Postoperative and Nonpostoperative Atrial Fibrillation in Routine Clinical Practice"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9906-7106","authenticated-orcid":false,"given":"Xiaoxi","family":"Yao","sequence":"first","affiliation":[{"name":"Robert D. and Patricia E. 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