{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T06:52:24Z","timestamp":1787813544023,"version":"build-2784847793"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"21","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,11,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Currently, there is a lack of evidence for the long\u2010term bioprosthetic valve durability of patients with bicuspid aortic valve (BAV) following transcatheter aortic valve replacement (TAVR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      This study aimed to evaluate hemodynamic outcome, structural valve deterioration, and bioprosthetic valve failure during long\u2010term follow\u2010up after TAVR in patients with BAV versus patients with tricuspid aortic valve (TAV). Patients with BAV and TAV who underwent TAVR between 2012 and 2020, with echocardiography followed for at least 3\u2009years, were included. Baseline characteristics, long\u2010term valve hemodynamic performance, structural valve deterioration, and bioprosthetic valve failure were compared between patients with BAV and TAV. A total of 170 patients with BAV and 145 patients with TAV were included. The mean duration of follow\u2010up for patients with BAV and TAV was 5.2\u00b11.8 and 5.0\u00b11.7\u2009years. No significant differences were observed in the rates of structural valve deterioration and bioprosthetic valve failure between patients with BAV and TAV: structural valve deterioration, BAV 20 (11.8%) versus TAV 16 (11.0%) at last follow\u2010up (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.861); bioprosthetic valve failure, BAV 3 (1.8%) versus TAV 7 (4.8%) at last follow\u2010up (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.196). More than moderate intravalvular aortic regurgitation (1.8% versus 4.8%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.196) and\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/paravalvular-leak\">paravalvular leak<\/jats:ext-link>\n                      (6.5% versus 3.4%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.305) were rare in both patients with BAV and patients with TAV.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">This study indicated satisfactory long\u2010term valve durability of TAVR in patients with BAV. Comparable hemodynamic outcome, structural valve deterioration, and bioprosthetic valve failure could be achieved in patients with BAV and TAV during long\u2010term follow\u2010up after TAVR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.035772","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T07:49:48Z","timestamp":1730188188000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Long\u2010Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0701-2393","authenticated-orcid":false,"given":"Hong\u2010De","family":"Li","sequence":"first","affiliation":[{"name":"West China Hospital, Sichuan University","place":["Chengdu, People\u2019s Republic of China"]},{"name":"West China Hospital, Sichuan 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