{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:03:43Z","timestamp":1784117023975,"version":"3.55.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"21","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,11,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Flow diversion has revolutionized the management of wide\u2010necked intracranial aneurysms (IAs). We aimed to assess the effectiveness and safety of the new generation 64\u2010wire Surpass Evolve for the treatment of unruptured small\/medium\u2010sized IAs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      This is a subanalysis from the SEASE (Safety and Effectiveness Assessment of the Surpass Evolve) registry, an observational cohort study including 15 academic institutions in North America and Europe between July 2020 and October 2022. Patients with wide\u2010necked saccular IAs, measuring &lt;12\u2009mm along the internal carotid artery and vertebrobasilar system, and treated with the Surpass Evolve were included. Primary effectiveness was complete occlusion (Raymond\u2010Roy class 1) at follow\u2010up (core laboratory adjudicated), and primary safety was major stroke (ischemic\/hemorrhagic) in the territory supplied by the target artery or death. A total of 129 cases with 135 IAs were included (median age 59\u2009years, 85.3% women). Median maximum IAs size and neck size were 5.1 and 3.9\u2009mm, respectively. Most IAs were in the internal carotid artery C6 (65.9%, 89\/135) and C7 (14.1%, 19\/135) segments. At a median follow\u2010up time of 10.2\u2009months (interquartile range, 6.4\u201312.8), complete occlusion was 77.1% (101\/131), \u226550% in\u2010stent stenosis was 8.8% (11\/125), and retreatment was 0.8% (1\/125). Major stroke and mortality were reported in 2 (1.6%) patients and 1 (0.8%) patient, respectively. Size was the only factor associated with higher odds of incomplete occlusion (adjusted odds ratio, 1.2 [95% CI, 1.02\u20131.5];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients with small\/medium\u2010sized IAs can be effectively treated using the Surpass Evolve, a new generation, 64\u2010wire, cobalt\u2010chromium flow diverter.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.036365","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T07:04:32Z","timestamp":1729839872000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Treatment of Unruptured Small and Medium\u2010Sized Wide Necked Aneurysms Using the 64\u2010Wire Surpass Evolve: A\u00a0Subanalysis From the SEASE International Registry"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1690-1084","authenticated-orcid":false,"given":"Mahmoud","family":"Dibas","sequence":"first","affiliation":[{"name":"University of Iowa Hospitals and Clinics","place":["Iowa City"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5326-1907","authenticated-orcid":false,"given":"Juan","family":"Vivanco\u2010Suarez","sequence":"additional","affiliation":[{"name":"University of Iowa Hospitals and Clinics","place":["Iowa City"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demetrius K.","family":"Lopes","sequence":"additional","affiliation":[{"name":"Advocate Aurora Health","place":["Park Ridge"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7195-5806","authenticated-orcid":false,"given":"Ricardo A.","family":"Hanel","sequence":"additional","affiliation":[{"name":"Baptist Neurological Institute","place":["Jacksonville"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8413-6954","authenticated-orcid":false,"given":"Aaron","family":"Rodriguez\u2010Calienes","sequence":"additional","affiliation":[{"name":"Universidad Cient\u00edfica del Sur","place":["Lima, Peru"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4227-0378","authenticated-orcid":false,"given":"Gustavo M.","family":"Cortez","sequence":"additional","affiliation":[{"name":"Baptist Neurological Institute","place":["Jacksonville"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7786-5668","authenticated-orcid":false,"given":"Johanna T.","family":"Fifi","sequence":"additional","affiliation":[{"name":"Mount Sinai Health System","place":["New York"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7728-9573","authenticated-orcid":false,"given":"Alex","family":"Devarajan","sequence":"additional","affiliation":[{"name":"Mount Sinai Health System","place":["New York"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3646-3635","authenticated-orcid":false,"given":"Gabor","family":"Toth","sequence":"additional","affiliation":[{"name":"Cleveland Clinic","place":["Cleveland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2989-5517","authenticated-orcid":false,"given":"Thomas E.","family":"Patterson","sequence":"additional","affiliation":[{"name":"Cleveland Clinic","place":["Cleveland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5130-1378","authenticated-orcid":false,"given":"David","family":"Altschul","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine","place":["Bronx"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor M.","family":"Pereira","sequence":"additional","affiliation":[{"name":"St Michael\u2019s Hospital","place":["Toronto, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Y. 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