{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:36:22Z","timestamp":1793136982417,"version":"4.5.0"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"21","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,11,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Septal myectomy and alcohol septal ablation (ASA) are septal reduction therapies for patients with symptomatic obstructive hypertrophic cardiomyopathy. Operator and hospital volume may influence outcomes, but contemporary data on this relationship are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      This retrospective cohort study used data from the Vizient Clinical Data Base (2016\u20132022). Patients with undergoing septal myectomy and ASA were identified using\n                      <jats:italic toggle=\"no\">International Classification of Diseases, Tenth Revision, Clinical Modification<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"no\">ICD\u201010\u2010CM<\/jats:italic>\n                      ) codes and stratified into low\u2010, medium\u2010, and high\u2010volume groups based on annualized operator and hospital volumes. The outcomes were 30\u2010day in\u2010hospital mortality and 90\u2010day readmission, analyzed using multivariable adjusted logistic and Cox models. Among 5725 patients with hypertrophic cardiomyopathy (3990 septal myectomy; 1735 ASA), most operators and hospitals performed &lt;10 procedures annually. For septal myectomy, low\u2010volume operators were associated with higher odds of 30\u2010day mortality (adjusted odds ratio [aOR], 1.86 [95% CI, 1.11\u20133.15]) and greater risk for 90\u2010day readmission (aOR, 1.51 [95% CI, 1.22\u20131.88]), and medium\u2010volume operators had higher odds of 30\u2010day mortality (aOR, 1.93 [95% CI, 1.05\u20133.55]). Medium\u2010volume hospitals had higher 30\u2010day mortality (aOR, 2.29 [95% CI, 1.32\u20133.99]), with low\u2010volume hospitals showing greater risk for 90\u2010day readmission (aOR, 1.60 [95% CI, 1.14\u20132.23]). For ASA, low\u2010 and medium\u2010volume operators had increased 30\u2010day mortality (aOR, 2.99 [95% CI, 1.15\u20137.75] and aOR, 3.86 [95% CI, 1.30\u201311.46]), but the risk of 90\u2010day readmission was similar. Hospital volumes did not significantly impact outcomes for ASA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Low operator and hospital volumes were associated with worse outcomes for septal reduction therapies, emphasizing the need to refer patients with hypertrophic cardiomyopathy to high\u2010volume centers with experienced operators.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.036387","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T07:05:22Z","timestamp":1729839922000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Procedural Volume and Outcomes After Septal Reduction Therapies in Hypertrophic Obstructive Cardiomyopathy"],"prefix":"10.1161","volume":"13","author":[{"given":"Nirav","family":"Patel","sequence":"first","affiliation":[{"name":"University of Alabama at Birmingham","place":["Birmingham"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3600-126X","authenticated-orcid":false,"given":"Naman S.","family":"Shetty","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital","place":["Boston"]},{"name":"Harvard Medical School","place":["Boston"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0309-6813","authenticated-orcid":false,"given":"Mokshad","family":"Gaonkar","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["Birmingham"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulla","family":"Shahid","sequence":"additional","affiliation":[{"name":"University of Alabama at 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