{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T03:07:08Z","timestamp":1790478428000,"version":"4.1.0"},"reference-count":58,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"20","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,10,15]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">The aim of this study was to characterize the burden of valvular heart disease (VHD)\u2010related heart failure (HF) in Group of 20 (G20) countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">Using data from the 2019 Global Burden of Disease Study, we estimated VHD\u2010related HF burdens (cases, age\u2010standardized prevalence rates, and years lived with disabilities rates) in G20 countries from 1990 to 2019 by age, sex, and sociodemographic index. The burden of VHD\u2010related HF increased in G20 countries from 1990 to 2019, exhibiting heterogeneity across VHD subtypes. In 2019, Italy, the United States, and the Russian Federation had the highest age\u2010standardized prevalence rates of nonrheumatic VHD\u2010related HF, whereas India, Brazil, and Mexico had the lowest. Rheumatic VHD\u2010related HF was most prevalent in China, India, and Italy, whereas the Republic of Korea, Brazil, and Turkey had the lowest. Nonrheumatic VHD\u2010related HF prevalence peaked among G20 countries in individuals \u226585\u2009years of age, whereas rheumatic VHD\u2010related HF peaked in those 75 to 84\u2009years of age in several countries, including China, India, the Russian Federation, Mexico, Argentina, and Turkey. Age\u2010standardized prevalence rates of nonrheumatic VHD\u2010related HF showed a decreasing trend, more pronounced in women, whereas rheumatic VHD\u2010related HF increased in both sexes, with a lower increase in men. Nonrheumatic VHD\u2010related HF burden correlated with age and sociodemographic index, whereas rheumatic VHD\u2010related HF burden was highest in middle sociodemographic index countries for those &lt;75\u2009years of age. Years lived with disabilities rates for VHD\u2010related HF represented about 9.0% of the overall burden across populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">The increasing burden of VHD\u2010related HF in G20 countries highlights the need for timely interventions to mitigate this growing public health challenge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.036462","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T07:16:36Z","timestamp":1728630996000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Burden and Temporal Trends of Valvular Heart Disease\u2010Related Heart Failure From 1990 to 2019 and Projection Up to 2030 in Group of 20 Countries: An Analysis for the Global Burden of Disease Study 2019"],"prefix":"10.1161","volume":"13","author":[{"given":"Shenghui","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Cardiology The Second Affiliated Hospital, School of Medicine, South China University of Technology Guangzhou China"},{"name":"Department of Cardiology Guangzhou First People\u2019s Hospital, South China University of Technology Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0508-0129","authenticated-orcid":false,"given":"Cheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Guangzhou First People\u2019s Hospital, South China University of Technology Guangzhou China"},{"name":"Department of Cardiology Guangzhou First People\u2019s Hospital, Guangzhou Medical University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingsheng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of 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