{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T13:43:08Z","timestamp":1763991788006,"version":"3.45.0"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">The risk of ischemic stroke hospitalization in patients with end\u2010stage kidney disease has declined over time, but data are limited, especially for hemorrhagic stroke trends. Race\u2010 and sex\u2010based differences have not been well studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>METHODS AND RESULTS<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      We conducted a retrospective cohort study using the US Renal Data System to examine the incidence of stroke among incident patients undergoing hemodialysis from 2006 to 2016. We identified 391\u2009195 new patients undergoing hemodialysis (mean age, 70.1\u2009years; 44.8% women) between 2006 and 2016. The incidence of any stroke per 100\u2009000 patients decreased from 2746 cases at 1\u2009year and 6823 cases at 3\u2009years during 2006 to 2009 to 1983 cases at 1\u2009year and 5162 cases at 3\u2009years in 2014 to 2016 (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). Women had higher stroke incidence than men (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). White adults had higher incidence compared with Black adults, Hispanic adults, and Other (Native American participants and those whose racial and ethnic identification did not align with the classifications) race (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). The risk decreased over the study period for both sexes and races, except \u201cOther\u201d race. Hemorrhagic stroke incidence was 409 cases at 1\u2009year and 1125 at 3\u2009years per 100\u2009000. No sex difference was observed at 1\u2009year, but women had higher 3\u2010year rates (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.005). Black and Hispanic adults had higher 3\u2010year hemorrhagic stroke rates than White adults (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). Decreases occurred only for women, Black adults, and Hispanic adults at 1\u2009year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">While the overall risk of stroke remains high after hemodialysis initiation, significant reductions in stroke risk have occurred over the past decade across sexes and racial groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.036468","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T06:42:28Z","timestamp":1742971348000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Nationwide Trends in Stroke Among Patients Undergoing Hemodialysis by Sex and Race: An Analysis From the US Renal Database"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5316-1874","authenticated-orcid":false,"given":"Zafar","family":"Ali","sequence":"first","affiliation":[{"name":"University of Kansas Medical Center","place":["Kansas City, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6883-5686","authenticated-orcid":false,"given":"Wan\u2010Chi","family":"Chan","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center","place":["Kansas City, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7774-2729","authenticated-orcid":false,"given":"Edward F.","family":"Ellerbeck","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center","place":["Kansas City, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2091-0875","authenticated-orcid":false,"given":"Reem A.","family":"Mustafa","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center","place":["Kansas City, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8812-722X","authenticated-orcid":false,"given":"Jinxiang","family":"Hu","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center","place":["Kansas City, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2440-9033","authenticated-orcid":false,"given":"Kamal","family":"Gupta","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center","place":["Kansas City, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30499-X"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000226604.10877.fc"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2008.07.003"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.08.1046"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2020.07.010"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.000691"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70193-5"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00101.x"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.asn.0000019641.41496.1e"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/13.8.2004"},{"key":"e_1_3_1_12_2","volume-title":"USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States","author":"United States Renal Data System","year":"2022","unstructured":"United States Renal Data System . 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