{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:55:10Z","timestamp":1787018110141,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"21","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,11,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Ambulatory ECG (AECG) monitoring is pivotal to the diagnosis of arrhythmias and can be performed with near \u201creal\u2010time\u201d notification of abnormalities. There are limited data on the relative benefit of real\u2010time monitoring compared with traditional Holter monitoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      This is a retrospective observational analysis of University of Utah Health patients who underwent ambulatory ECG studies from 2010 to 2022. The study cohort was stratified by patients with an ambulatory ECG that provides real\u2010time event notification (non\u2010Holter) versus those who do not (Holter). The outcomes were cardiac implantable electronic device procedure, ablation procedure, emergency department\/hospitalization visit, and initiation of anticoagulation out to 6\u2009months. We identified 20\u2009259 patients, 16\u2009650 with non\u2010Holter studies and 3609 with Holter studies. Holter patients were younger (mean 52 versus 55,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001), more often women (60.2% versus 57%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001), and had lower mean CHADS\n                      <jats:sub>2<\/jats:sub>\n                      \u2010VA\n                      <jats:sub>2<\/jats:sub>\n                      Sc scores (1.7 versus 2.1,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). The median time to ablation procedure was 74 versus 72 (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.5), for Holter versus non\u2010Holter, respectively. Median days to new cardiac implantable electronic device implantation was 54\u2009days versus 52 (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.6); initiation of anticoagulation among patients not already treated was 42 versus 31\u2009days (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.03). Time to first emergency department visit or hospitalization was 63 versus 57 (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.6). In multivariable models, there were no significant differences in time to intervention between Holter and non\u2010Holter for each outcome.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Real\u2010time monitoring demonstrates mixed results in terms of reducing time to intervention, with the significant benefit limited to oral anticoagulation initiation. It is time to revisit clinical scenarios where real\u2010time ambulatory monitoring may not improve health care efficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.124.036520","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T06:31:13Z","timestamp":1729578673000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Real\u2010Time Ambulatory ECG Does Not Expedite Care"],"prefix":"10.1161","volume":"13","author":[{"given":"Melissa","family":"Feuerborn","sequence":"first","affiliation":[{"name":"University of Utah Health Sciences Center","place":["Salt Lake City"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Torre","sequence":"additional","affiliation":[{"name":"University of Utah Health Sciences Center","place":["Salt Lake City"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-4008","authenticated-orcid":false,"given":"Ann","family":"Lyons","sequence":"additional","affiliation":[{"name":"University of Utah Health Sciences Center","place":["Salt Lake City"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5349-0136","authenticated-orcid":false,"given":"Thomas Jared","family":"Bunch","sequence":"additional","affiliation":[{"name":"University of Utah Health Sciences Center","place":["Salt Lake City"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4729-7820","authenticated-orcid":false,"given":"Benjamin A.","family":"Steinberg","sequence":"additional","affiliation":[{"name":"University of Utah Health Sciences Center","place":["Salt Lake City"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccep.2021.04.003"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.2147\/MDER.S54038"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000160417.39497.a9"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000182534.19832.83"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz293"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2023.12.002"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-1_part_1-199601010-00003"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.10.078"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.045968"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2021.11.027"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2013.10.003"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.10.014"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.124.036520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T11:03:27Z","timestamp":1784113407000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.124.036520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,5]]},"references-count":13,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2024,11,5]]}},"alternative-id":["10.1161\/JAHA.124.036520"],"URL":"https:\/\/doi.org\/10.1161\/jaha.124.036520","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,5]]},"assertion":[{"value":"2024-05-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e036520"}}