{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:20:44Z","timestamp":1790731244909,"version":"4.1.0"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"22","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2024,11,19]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Lymphatic disorders such as protein\u2010losing enteropathy, plastic bronchitis, and chylothorax are important complications of the Fontan circulation and ultimately result in an increased risk of early death. Several European centers are now performing lymphatic procedures. The aim of this study is to map the extent of these lymphatic disorders and treatments provided across European pediatric cardiology centers.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">A survey was circulated to 49 European pediatric cardiology centers consisting of 37 questions including a mix of binary, categorical, and continuous variables. Thirty\u2010one centers (63%) participated in the study, performing a median of 250 (interquartile range, 178 \u2010 313) cardiopulmonary bypass procedures per year. Chylothorax emerged as the most prevalent lymphatic disorder\u00a0followed by protein\u2010losing enteropathy and plastic bronchitis. The most common diagnostic investigation method was noncontrast magnetic resonance lymphangiography (52%). Eleven centers (35%) conducted lymphatic interventions with a median of 3 (interquartile range, 1 \u2010 4) procedures per year and 12 (interquartile range, 5 \u2010 15) interventions in total per center.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">This study confirms the rarity of and variation in treatment approaches for lymphatic disorders across Europe. With at least 11 centers offering lymphatic interventions, the adoption of these procedures is on the rise in Europe. To improve the quality of care and treatment outcomes for these complex patients, it is crucial to consider evidence\u2010based lymphatic diagnostics, interventional lymphatic procedures, and the centralization of services in Europe.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.036597","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T10:18:30Z","timestamp":1730974710000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Lymphatic Disorder Management in Pediatric Patients With Congenital Heart Disease in European Pediatric Cardiology Centers: Current Status, Disparities, and Future Considerations"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7012-3354","authenticated-orcid":false,"given":"Sanam","family":"Safi","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital of Copenhagen, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8047-0015","authenticated-orcid":false,"given":"Vibeke E.","family":"Hjortdal","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital of Copenhagen, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4595-5922","authenticated-orcid":false,"given":"Marc","family":"Gewillig","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1448-1012","authenticated-orcid":false,"given":"Owen","family":"Miller","sequence":"additional","affiliation":[{"name":"Department Paediatric Cardiology Evelina London Children\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7303-5808","authenticated-orcid":false,"given":"Mohammad Ryan","family":"Abumehdi","sequence":"additional","affiliation":[{"name":"Department Pediatric Cardiology Royal Brompton Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2430-6480","authenticated-orcid":false,"given":"Massimiliano","family":"Cantinotti","sequence":"additional","affiliation":[{"name":"Fondazione CNR\u2010Regione Toscana G. 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