{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T20:16:10Z","timestamp":1782504970291,"version":"3.54.5"},"reference-count":48,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Recent technologies enable real\u2010time 3\u2010dimensional intracardiac echocardiography (ICE) with the advantages of 2\u2010dimensional ICE and imaging capabilities of transesophageal echocardiography. The purpose of this study is to evaluate the real\u2010world, multicenter safety and performance of a novel 3\u2010dimensional ICE system in a variety of cardiac interventions used in standard clinical practice.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">This prospective, multicenter, observational, single\u2010arm study enrolled patients who were scheduled for an invasive cardiac procedure involving guidance with ICE and followed until discharge or \u226448\u2009hours postprocedure. Intracardiac imaging was performed with the 3\u2010dimensional ICE catheter, VeriSight Pro (Philips Inc.). Fluoroscopy was used in all cases and transesophageal echocardiography was used in some cases. The primary safety end point was device\u2010related adverse events. The primary efficacy end point included technical success, imaging success, and clinical success.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Between October 2021 and November 2022, 155 patients were enrolled and screened. Percutaneous interventions performed included atrial septal defect\/patent foramen ovale closures, left atrial appendage occlusion, catheter ablations, and valve procedures. No adverse events were related to the device or procedure. The technical, imaging, and clinical success rates were 98.7% (95% CI, 95.4%\u201399.8%), 96.1% (95% CI, 91.8%\u201398.6%), 94.8% (95% CI, 91.8%\u201398.6%), respectively. Overall, the VeriSight Pro ICE image quality was assessed to be \u201cacceptable\u201d or greater in relation to reference image modality among 96.2% (149 of 155) of procedures.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">VeriSight ICE imaging is safe and effective in the guidance of a wide variety of percutaneous cardiovascular procedures and has provided successful and high\u2010quality imaging of cardiac structures.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.037019","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T10:32:06Z","timestamp":1741861926000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Multicenter Experience With a Novel Real\u2010Time 3\u2010Dimensional Intracardiac Echocardiography Catheter to Guide Interventional Cardiac Procedures"],"prefix":"10.1161","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3847-0959","authenticated-orcid":false,"given":"Mohamad Adnan","family":"Alkhouli","sequence":"first","affiliation":[{"name":"Mayo Clinic","place":["Rochester, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8423-0169","authenticated-orcid":false,"given":"John D.","family":"Carroll","sequence":"additional","affiliation":[{"name":"University of Colorado Hospital","place":["Aurora, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3587-9006","authenticated-orcid":false,"given":"Aken A.","family":"Desai","sequence":"additional","affiliation":[{"name":"University of Colorado Hospital","place":["Aurora, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8363-6757","authenticated-orcid":false,"given":"Yu\u2010Rong","family":"Gao","sequence":"additional","affiliation":[{"name":"Philips Image Guided Therapy Corporation","place":["Colorado Springs, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomnema","family":"Xiong","sequence":"additional","affiliation":[{"name":"Philips Image Guided Therapy Corporation","place":["Colorado Springs, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5487-0728","authenticated-orcid":false,"given":"Andrea","family":"Natale","sequence":"additional","affiliation":[{"name":"Texas Cardiac Arrhythmia Institute, St. David\u2019s Medical Center","place":["Austin, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2757-6830","authenticated-orcid":false,"given":"Ignacio","family":"Inglessis\u2010Azuaje","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital","place":["Boston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2129-0401","authenticated-orcid":false,"given":"Bradley P.","family":"Knight","sequence":"additional","affiliation":[{"name":"Northwestern University, Feinberg School of Medicine","place":["Chicago, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.04.037"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.10.035"},{"key":"e_1_3_2_4_2","first-page":"567","article-title":"Transoesophageal echocardiography related complications","volume":"53","author":"Mathur SK","year":"2009","unstructured":"Mathur SK, Singh P. 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