{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:06:57Z","timestamp":1790644017791,"version":"4.1.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,5,20]]},"abstract":"<jats:sec id=\"jah310771-sec-0001\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Obstructive sleep apnea represents an arrhythmia recurrence risk following catheter ablation of atrial fibrillation (AF). Continuous positive airway pressure (CPAP) therapy may reduce recurrence, but individual adherence to CPAP varies, potentially leading to inconsistent results across studies.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah310771-sec-0002\" xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We analyzed the impact of CPAP adherence on AF recurrence after catheter ablation in patients with severe obstructive sleep apnea (apnea\u2010hypopnea index \u226530). Of 1864 consecutive patients undergoing an index catheter ablation of AF, those with severe obstructive sleep apnea were enrolled in this study. Recurrence rates were compared between patients with and without long\u2010term CPAP adherence (&gt;1\u2010year use). CPAP use was monitored via telemonitoring and outpatient follow\u2010ups. Among 466 patients, 157 (33.7%) adhered to CPAP long\u2010term, reducing apnea\u2010hypopnea index from 37.7\u00b115.3 to 3.9\u00b13.1 (\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              &lt;0.0001). While AF recurrence rates within the first year post\u2013catheter ablation were similar between the groups, very late recurrence (beyond 1 year) was significantly lower in patients with long\u2010term CPAP treatment than in those without (7.6% versus 21.6%, log\u2010rank\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              =0.0002). Even after adjusting for potential confounders, long\u2010term CPAP treatment was associated with a lower risk of very late recurrence (adjusted hazard ratio, 0.30 [95% CI, 0.14\u20130.57]).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah310771-sec-0004\" xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">In patients with severe obstructive sleep apnea at baseline, AF recurrence rates within 1\u2010year postablation were similar regardless of CPAP adherence. However, long\u2010term CPAP therapy was associated with a reduced AF recurrence rate in the subsequent period.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.038742","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T09:26:32Z","timestamp":1747301192000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Impact of Long\u2010Term CPAP Adherence on Recurrence After Atrial Fibrillation Ablation in Patients With Severe Sleep Apnea"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8324-1728","authenticated-orcid":false,"given":"Nobuaki","family":"Tanaka","sequence":"first","affiliation":[{"name":"Cardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3190-7313","authenticated-orcid":false,"given":"Masato","family":"Okada","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2628-5601","authenticated-orcid":false,"given":"Yuko","family":"Hirao","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Sakurabashi Watanabe Advanced Healthcare Hospital","place":["Osaka, 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