{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:49:31Z","timestamp":1767016171382,"version":"3.41.2"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,6,3]]},"abstract":"<jats:sec id=\"jah310966-sec-0001\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Abnormal exercise blood pressure (BP) responses are associated with hypertension and cardiovascular disease, but their relationship with home BP over a mid\u2010 to long\u2010term time span is unknown.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah310966-sec-0002\" xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">At an FHS (Framingham Heart Study) research examination (2016\u20132019), participants underwent maximum incremental ramp cycle ergometry cardiopulmonary exercise testing with BP measured every 2\u2009minutes. At the same exam, English\u2010speaking participants enrolled in the electronic FHS with an iPhone were provided with a digital BP cuff to measure home BP weekly for 1\u2009year. Linear regression models examined associations of exercise BP with average home systolic BP (SBP), home\u2010based hypertension, and week\u2010to\u2010week average real variability of home SBP, over 1\u2010year follow\u2010up. Participants with &lt;3\u2009weeks of BP return were excluded.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah310966-sec-0003\" xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Among 808 participants (mean age, 53\u2009years; 58% women; 92% White individuals; 47% hypertension), higher exercise BP responses (peak SBP, SBP at 75\u2009W, SBP\/workload slope, peak diastolic BP, and diastolic BP at 75\u2009W) were associated with higher average home SBP. Higher peak diastolic BP was associated with a greater risk for home hypertension. Additionally, higher SBP\/workload slope and peak diastolic BP were associated with elevated average real variability of home SBP only in participants without antihypertensive use.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah310966-sec-0004\" xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Higher exercise BP responses were associated with higher average home\u2010based BP, greater home\u2010based hypertension risk, and increased home\u2010based BP variability over a mid\u2010 to long\u2010term time span. However, these associations may vary by antihypertensive medication use. Exercise BP may play an important role in hypertension prevention and treatment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.039457","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T11:33:41Z","timestamp":1748950421000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study"],"prefix":"10.1161","volume":"14","author":[{"given":"Xuzhi","family":"Wang","sequence":"first","affiliation":[{"name":"Boston University School of Public Health","place":["Boston, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2318-7539","authenticated-orcid":false,"given":"Yuankai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Boston University School of Public 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