{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T03:02:32Z","timestamp":1785294152942,"version":"3.55.0"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,8,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Currently, the sex\u2010differentiated outcome after percutaneous coronary intervention (PCI) favors male sex in most studies. In this study, we aimed to investigate the age\u2010adjusted impact of sex on long\u2010term outcome.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">The study was an observational, prospective, multicenter, cohort study with pooling of 5\u2010year results of the randomized controlled all\u2010comer stent trials SORT OUT (Scandinavian Organization for Randomized Trials With Clinical Outcome) III, V, VI, VII, VIII, and IX conducted from 2006 to 2017. All patients were followed for 5\u2009years. The predefined main outcome was a major adverse cardiac event (MACE); a composite end point comprising all\u2010cause death, spontaneous myocardial infarction, and target lesion revascularization assessed by a clinical event committee. MACE difference across sex was assessed by incidence rate ratios at 5\u2009years adjusted for age and predefined risk factors.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">In total, 15\u2009242 patients (women, 3729 [24.5%]) with a mean age of 67.8\u00b111.0\u2009years were included in the study, with 0.2% lost to follow\u2010up. Compared with men, women were older (women, 67.8\u00b111.0 years; men, 64.8\u00b110.7\u2009years), had more hypertension and dyslipidemia but less previous MI and revascularization. MACEs occurred in 747 (21.8%) of the women and 2196 (20.5%) of the men at 5\u2009years (unadjusted incidence rate ratio, 1.07 [95% CI, 0.98\u20131.16]; and adjusted incidence rate ratio, 0.91 [95% CI, 0.84\u20130.99]). Female sex was not associated with an increased risk in any of the individual MACE components.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Female sex was not associated with a poorer long\u2010term outcome than male sex after treatment for coronary artery disease with percutaneous coronary intervention in MACEs or any of the individual components.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.039758","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T06:20:27Z","timestamp":1752819627000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Sex\u2010Stratified Long\u2010Term Outcome After Percutaneous Coronary Intervention: A\u00a0Pooled Analysis of the SORT OUT All\u2010Comer 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Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4838-2429","authenticated-orcid":false,"given":"Lisette O.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Odense University Hospital","place":["Odense C, Denmark"]},{"name":"University of Southern Denmark","place":["Odense M, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8740-4862","authenticated-orcid":false,"given":"Evald H.","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Aarhus University Hospital","place":["Aarhus N, Denmark"]},{"name":"Aarhus University","place":["Aarhus N, 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