{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T07:55:46Z","timestamp":1774511746497,"version":"3.50.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,8,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Children with congenital heart disease undergoing noncardiac surgery are at increased risk of perioperative complications. The objectives of our study are (1) to describe the prevalence and characteristics of children undergoing noncardiac surgery in the presence or absence of COVID\u201019 infection and (2) describe the association between preoperative diagnosis of COVID\u201019 and outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">We identified all children who underwent surgery between 2017 and 2022 in the American College of Surgeons National Surgical Quality Improvement Program pediatric database. Starting in 2021, the presence of a preoperative diagnosis of COVID\u201019 was reported in the database. The outcomes included 30\u2010day mortality and the incidence of the following major postoperative outcomes: cardiac arrest, reintubation, pneumonia, sepsis, and readmission. A composite end point that includes the presence of at least 1 of the abovementioned complications was created.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We identified 2919 patients with a preoperative diagnosis of COVID\u201019 versus 537\u2009622 without. Patients with a preoperative diagnosis of COVID\u201019 underwent emergent procedures more often (64% versus 29%). Using multivariable logistic regression, the presence of preoperative diagnosis of COVID\u201019 increased the incidence of the composite endpoint (odds ratio [OR], 1.37 [95% CI, 1.19\u20131.56];\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              &lt;0.001), as did the presence of CHD (OR, 2.06 [95% CI, 2.00\u20132.13];\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              &lt;0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Our study describes the prevalence and characteristics of children with congenital heart disease undergoing noncardiac surgery during the COVID\u201019 pandemic. We report that the preoperative diagnosis of COVID\u201019 and the presence of congenital heart disease significantly increased the risk of complications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.124.040182","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T12:01:10Z","timestamp":1752753670000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence, Characteristics, and Outcomes of Children With Congenital Heart Disease Undergoing Noncardiac Surgery in the Presence or Absence of COVID\u201019 Infection During the Pandemic"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1093-4523","authenticated-orcid":false,"given":"David","family":"Faraoni","sequence":"first","affiliation":[{"name":"Boston Children\u2019s Hospital, Harvard Medical School","place":["Boston, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"DiNardo","sequence":"additional","affiliation":[{"name":"Boston Children\u2019s Hospital, Harvard Medical School","place":["Boston, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2321-3987","authenticated-orcid":false,"given":"Viviane G.","family":"Nasr","sequence":"additional","affiliation":[{"name":"Boston Children\u2019s Hospital, Harvard Medical School","place":["Boston, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000005015"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001064"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-021-02751-6"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4103\/apc.apc_133_21"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.07.005"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000183348.15117.ab"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.11.057"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001500"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004906"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjcpc.2023.09.002"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/21501351221085966"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017580"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-023-04058-2"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.057833"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2023-002415"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.11967"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951120003741"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.701375"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/wjps-2021-000299"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/17407745241276130"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.124.040182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T12:12:10Z","timestamp":1756296730000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.124.040182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,5]]},"references-count":20,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2025,8,5]]}},"alternative-id":["10.1161\/JAHA.124.040182"],"URL":"https:\/\/doi.org\/10.1161\/jaha.124.040182","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,5]]},"assertion":[{"value":"2024-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e040182"}}