{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:48:26Z","timestamp":1789778906821,"version":"4.0.1"},"reference-count":47,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"24","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,12,16]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">There is conflicting evidence on the time trends of stroke incidence in younger adults. We aimed to explore time trends in the incidence of stroke, stroke subtypes, and transient ischemic attack in different age groups in Norway the past 2 decades.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this nationwide registry\u2010based cohort study, we identified incident stroke cases from hospitalizations with stroke (ischemic stroke, intracerebral hemorrhage and unspecified stroke), transient ischemic attack, or out\u2010of\u2010hospital deaths due to stroke. Included individuals were aged \u226515\u2009years with no prior hospitalization for stroke during the past 7\u2009years. Incidence per 100\u2009000 population was age\u2010standardized and presented by year, sex, and age group. Average annual percentage changes in incidence were estimated using weighted log\u2010linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">From 2001 to 2021, we identified 229\u2009857 incident total stroke cases (49.2% women) among 5\u2009691\u2009495 individuals in the Norwegian adult population. Incidence per 100\u2009000 population decreased over time for all stroke subtypes in both men and women. However, the incidence of ischemic stroke for men aged &lt;35\u2009years increased annually by 1.6% (95% CI, 0.3\u20132.8). For intracerebral hemorrhage, the incidence was stable in younger men and women and the oldest women. For transient ischemic attack, both sexes experienced a sharp rise in the incidence until 2012, followed by a substantial decrease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Total stroke incidence declined from 2001 to 2021. However, less favorable time trends were observed in younger age groups, with a worrisome increase in ischemic stroke incidence among men aged 15 to 34\u2009years. These trends are concerning and need further investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.041029","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T10:40:01Z","timestamp":1765449601000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Nationwide Trends in Incidence of Stroke and Transient Ischemic Attack in Younger and Older Adults in Norway 2001 to 2021"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8826-7984","authenticated-orcid":false,"given":"Elisabeth","family":"Kvalvaag","sequence":"first","affiliation":[{"name":"Norwegian Institute of Public Health","place":["Oslo, Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2379-9906","authenticated-orcid":false,"given":"Vidar","family":"Hjellvik","sequence":"additional","affiliation":[{"name":"Norwegian Institute of Public Health","place":["Oslo, Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Kjerpeseth","sequence":"additional","affiliation":[{"name":"Norwegian Institute of Public Health","place":["Oslo, Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannicke","family":"Igland","sequence":"additional","affiliation":[{"name":"University of Bergen","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanne","family":"Ellekj\u00e6r","sequence":"additional","affiliation":[{"name":"Norwegian University of Science and Technology","place":["Trondheim, Norway"]},{"name":"St. Olav\u2019s Hospital","place":["Trondheim, 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