{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:28:36Z","timestamp":1792819716367,"version":"4.5.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,9,2]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Infective endocarditis (IE) is a serious and potentially lethal condition in patients with end\u2010stage renal disease (ESRD). This study aimed to describe the clinical features, provide epidemiology information, and compare short and long\u2010term outcomes of IE in patients with ESRD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients who were admitted due to IE from 2001 to 2021 were identified from Taiwan's National Health Insurance Research Database and grouped based on whether they were undergoing chronic dialysis with ESRD. Primary outcomes were surgical rate during the index IE hospitalization, in\u2010hospital death, and all\u2010cause death after surviving to discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      A total of 27\u2009336 patients were included, with 3258 (11.9%) receiving dialysis. The surgical rate significantly increased over years in both the groups with and without ESRD. In\u2010hospital and late mortalities were significantly higher in patients with ESRD (32.9% versus 16.9%, and 76.0% versus 48.1%, respectively). The predominant pathogen was methicillin\u2010resistant\n                      <jats:italic toggle=\"no\">Staphylococcus aureus<\/jats:italic>\n                      , significantly higher in patients with ESRD (56.7% versus 32.8%). The vintage, type of hemodialysis access (tunnels, grafts, or fistulas), and initial dialysis modality were not correlated to the risk of in\u2010hospital mortality of patients with IE with ESRD. Patients who received valve surgery had better long\u2010term survival than those who did not receive in either the groups with and without ESRD and non\u2010ESRD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients with ESRD have higher in\u2010hospital and late mortality rates, more complications, and a higher recurrence rate of IE than patients without ESRD. The long\u2010term survival rates were higher in both the groups with and without ESRD and non\u2010ESRD who underwent surgeries for IE; therefore, surgery may be considered if the patient's condition permits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.041724","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T05:23:07Z","timestamp":1755926587000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Outcomes of End Stage Renal Disease in Patients With Infective Endocarditis: A\u00a0Nationwide Population\u2010Based Study"],"prefix":"10.1161","volume":"14","author":[{"given":"Hao\u2010Chen","family":"Hung","sequence":"first","affiliation":[{"name":"Chang Gung University, Linkou Chang Gung Memorial Hospital","place":["Taoyuan City, 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