{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T20:25:01Z","timestamp":1784492701675,"version":"3.55.0"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,10,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The prognosis of heart failure (HF) from ischemic heart disease (IHD) is generally worse than from dilated cardiomyopathy (DCM). The impact of prior sarcoidosis on HF outcomes is unknown. We evaluated the prognostic impact of sarcoidosis in HF compared with IHD\u2010HF and DCM\u2010HF using SwedeHF (Swedish Heart Failure Registry).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">We identified patients with sarcoidosis before HF diagnosis (SC\u2010HF) and propensity\u2010matched them to patients with DCM\u2010HF or IHD\u2010HF between 2003 and 2020. The primary outcome was all\u2010cause mortality; secondary outcomes were cardiovascular death and hospital readmission.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              A total of 422 patients with SC\u2010HF, 6913 with DCM\u2010HF, and 47\u2009164 with IHD\u2010HF were eligible. After 1:2 matching, 365 patients with SC\u2010HF (median follow\u2010up 2.9\u2009years) were compared with 730 with DCM\u2010HF (3.6\u2009years), and 418 with SC\u2010HF (2.8\u2009years) with 836 with IHD\u2010HF (3.6\u2009years). Baseline characteristics were well balanced. Patients with SC\u2010HF had more comorbidities than DCM\u2010HF but fewer than IHD\u2010HF. One\u2010year all\u2010cause mortality was higher in patients with SC\u2010HF than DCM\u2010HF (12.9% versus 8.6%; hazard ratio [HR, 1.51] [95% CI, 1.04\u20132.21];\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              =0.031), along with higher readmission rates. Compared patients with IHD\u2010HF, those with SC\u2010HF also showed higher 1\u2010year mortality (14.8% versus 9.7%; HR, 1.58 [95% CI, 1.14\u20132.20];\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              =0.006). Similar relative risks were observed across full follow\u2010up.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Sarcoidosis\u2010associated HF is linked to significantly higher mortality than both DCM and IHD and to higher morbidity than DCM. These findings underscore the need for heightened clinical attention and may warrant tailored management strategies for this high\u2010risk group.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.125.041944","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T10:33:38Z","timestamp":1759228418000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Increased Mortality and Morbidity in Patients With Heart Failure With Sarcoidosis Compared With Other Causes: A Propensity\u2010Matched Nationwide Cohort Study"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3341-2434","authenticated-orcid":false,"given":"Entela","family":"Bollano","sequence":"first","affiliation":[{"name":"Sahlgrenska University Hospital","place":["Gothenburg, Sweden"]},{"name":"University of Gothenburg","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1636-870X","authenticated-orcid":false,"given":"Michael","family":"Fu","sequence":"additional","affiliation":[{"name":"University of Gothenburg","place":["Sweden"]},{"name":"Sahlgrenska University Hospital\/\u00d6stra, Region V\u00e4stra G\u00f6taland","place":["Gothenburg, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2224-3236","authenticated-orcid":false,"given":"Aldina","family":"Pivodic","sequence":"additional","affiliation":[{"name":"APNC Sweden","place":["M\u00f6lndal, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7125-9747","authenticated-orcid":false,"given":"Christian L.","family":"Polte","sequence":"additional","affiliation":[{"name":"University of Gothenburg","place":["Sweden"]},{"name":"Sahlgrenska University Hospital","place":["Gothenburg, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6353-8041","authenticated-orcid":false,"given":"Ulf","family":"Dahlstr\u00f6m","sequence":"additional","affiliation":[{"name":"Link\u00f6ping University","place":["Link\u00f6ping, Sweden"]},{"name":"Link\u00f6ping University","place":["Link\u00f6ping, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8287-2448","authenticated-orcid":false,"given":"Emanuele","family":"Bobbio","sequence":"additional","affiliation":[{"name":"Sahlgrenska University Hospital","place":["Gothenburg, Sweden"]},{"name":"University of Gothenburg","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/heart.83.5.596"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2012.07.011"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","unstructured":"Authors\/Task Force M McDonagh TA Metra M Adamo M Gardner RS Baumbach A B\u00f6hm M Burri H Butler J \u010celutkien\u0117 J et\u00a0al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). 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