{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:42:40Z","timestamp":1793835760473,"version":"4.6.1"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"14","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,7,15]]},"abstract":"<jats:sec id=\"jah311169-sec-0001\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Atrial fibrillation (AF) is often underdiagnosed and undertreated by noncardiologists. This study evaluated whether artificial intelligence\u2013enabled ECG (AI\u2010ECG) alerts could improve AF diagnosis and non\u2013vitamin K antagonist oral anticoagulant prescriptions by noncardiologists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"jah311169-sec-0002\" xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this open\u2010label, cluster randomized controlled trial (NCT05127460) at 2 hospitals in Taiwan, noncardiologists were randomized to an intervention group (AI\u2010ECG alerts) or control group (usual care). Alerts were sent to physicians when AI\u2010ECG identified AF in emergency or hospitalized patients at risk of stroke (CHA\u2082DS\u2082\u2010VASc \u22651 for men, \u22652 for women), excluding those with prior AF or oral anticoagulant use. Primary end points included a non\u2013vitamin K antagonist oral anticoagulant prescription within 90\u2009days after discharge, new AF diagnosis, echocardiogram arrangements, and cardiologist visits. Secondary end points were ischemic stroke, cardiovascular death, and all\u2010cause death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"jah311169-sec-0003\" xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">A total of 8857 and 8960 patients were treated by 120 and 113 noncardiologists in the intervention and control groups, respectively; 275 and 245 patients had AI\u2010detected AF. The non\u2013vitamin K antagonist oral anticoagulant prescription rate was significantly higher in the intervention group (23.3% versus 12.0%; hazard ratio [HR], 1.85 [95% CI, 1.11\u20133.07]). The intervention group also had a higher rate of AF diagnosis (HR, 1.40 [95% CI, 1.03\u20131.90]). No significant differences were observed in echocardiogram arrangements, cardiologist visits, or the rates of ischemic stroke, cardiovascular death, and all\u2010cause death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"jah311169-sec-0004\" xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">An AI\u2010ECG alert for AF identification promoted non\u2013vitamin K antagonist oral anticoagulant prescriptions among noncardiologists, thus reducing the disparity in AF care quality between cardiologists and noncardiologists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"jah311169-sec-0005\" xml:lang=\"en\">\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT05127460?cond=NCT05127460&amp;rank=1\">https:\/\/clinicaltrials.gov\/<\/jats:ext-link>\n                      ; Unique identifier: NCT05127460.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.042106","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T01:11:52Z","timestamp":1751591512000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Artificial Intelligence\u2013Enabled ECGs for Atrial Fibrillation Identification and Enhanced Oral Anticoagulant Adoption: A Pragmatic Randomized Clinical Trial"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3817-4079","authenticated-orcid":false,"given":"Wei\u2010Ting","family":"Liu","sequence":"first","affiliation":[{"name":"Tri\u2010Service General Hospital, National Defense Medical Center","place":["Taipei, Taiwan, 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