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In this study, we hypothesized that patients receiving more comprehensive diagnostic workup have better outcomes, regardless of their care setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Studies on the workup process of patients with TIA and the 90\u2010day post\u2010TIA ischemic stroke incidence were searched. Eligible studies were scored 1 to 4 based on the number of diagnostic workups (head computed tomography scan, brain magnetic resonance imaging, and cerebrovascular imaging) and the involvement of a neurology provider in the diagnosis process.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Thirty\u2010eight studies were included for meta\u2010analysis. The overall 90\u2010day post\u2010TIA ischemic stroke risk was estimated to be 5% (95% CI, 4.9%\u20135.1%). Our meta\u2010analysis showed that studies with higher scores\u2014provided more comprehensive diagnostic workups by neurology providers\u2014had a lower risk of 90\u2010day post\u2010TIA ischemic stroke (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). The post\u2010TIA ischemic stroke risk was 8.4% (95% CI, 6.4%\u201310.8%) among studies with a score of \u201c1, 5.3% (95% CI, 5.2%\u20135.5%) among studies with a score of 2, 2.9% (95% CI: 2.7%\u20133.2%) among studies with a score of 3, and 3.2% (95% CI, 2.5%\u20134%) among studies with a score of 4. The difference between studies with a score of 3 and \u201d4 was not statistically significant (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.524). Moreover, studies with more comprehensive cardiac examinations had lower 90\u2010day post\u2010TIA ischemic stroke risk (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Our findings highlight that a more comprehensive diagnostic workup\u2014neuroimaging, cerebrovascular studies, and cardiac examinations\u2014of patients with TIA delivered by neurology providers might improve their outcomes by reducing the risk of 90\u2010day post\u2010TIA ischemic stroke, regardless of the care setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.042175","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:46:29Z","timestamp":1761648389000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Risk of Ischemic Stroke After Transient Ischemic Attack in Patients Receiving Comprehensive Versus Noncomprehensive Diagnostic Workup: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8448-1539","authenticated-orcid":false,"given":"Seyyed Sina","family":"Hejazian","sequence":"first","affiliation":[{"name":"The Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2116-9492","authenticated-orcid":false,"given":"Shima","family":"Shahjouei","sequence":"additional","affiliation":[{"name":"The Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza Vafaei","family":"Sadr","sequence":"additional","affiliation":[{"name":"Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5603-1732","authenticated-orcid":false,"given":"Ajith","family":"Vemuri","sequence":"additional","affiliation":[{"name":"The Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4447-501X","authenticated-orcid":false,"given":"Sasan","family":"Bahrami","sequence":"additional","affiliation":[{"name":"The Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7689-933X","authenticated-orcid":false,"given":"Vida","family":"Abedi","sequence":"additional","affiliation":[{"name":"Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9477-0094","authenticated-orcid":false,"given":"Ramin","family":"Zand","sequence":"additional","affiliation":[{"name":"The Pennsylvania State University","place":["Hershey, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000375"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.26867"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000166839"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.106.475525"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12134511"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.36644"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.029858"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2022.05.018"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-4-1"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"e_1_3_2_12_2","unstructured":"Higgins JP Lasserson T Chandler J Tovey D Churchill R. 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