{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T05:20:09Z","timestamp":1787721609137,"version":"build-2784847793"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,7,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">High bleeding risk (HBR) is associated with an increased risk of both ischemic and bleeding events and is known to have a worse prognosis than non\u2010HBR in patients with acute myocardial infarction. However, data regarding the prognostic impact of complete revascularization (CR) in acute myocardial infarction and multivessel disease patients complicated by HBR remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">A total of 13\u2009460 patients with acute myocardial infarction and multivessel disease who underwent successful percutaneous coronary intervention for infarct\u2010related artery were selected from the nationwide Korean registry from 2011 to 2020. Primary outcome was major adverse cardiac and cerebrovascular events during 3\u2009years of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Of the 13\u2009460 patients, 4401 (32.7%) were classified as the group with HBR according to modified Academic Research Consortium\u2010HBR criteria and 1577 patients (35.8%) underwent CR. Among the group without HBR, 3911 patients (43.2%) underwent CR for noninfarct\u2010related artery. The group with HBR had significantly higher risk of major adverse cardiac and cerebrovascular events (non\u2010HBR versus HBR; 16.4% versus 35.7%; adjusted hazard ratio [HR], 1.70 [95% CI, 1.56\u20131.85];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001) and Bleeding Academic Research Consortium type 2 or greater bleeding (4.5% versus 10.4%; adjusted HR, 1.63 [95% CI, 1.38\u20131.94];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001) than the group without HBR. Patients who underwent CR were associated with lower risk of major adverse cardiac and cerebrovascular events at 3\u2009years than those with incomplete revascularization in both groups with HBR (40.0% versus 28.1%, adjusted HR, 0.65 [95% CI, 0.55\u20130.75],\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001) and without HBR (19.0% versus 13.1%, adjusted HR, 0.71 [95% CI, 0.63\u20130.80],\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001). The incidence of bleeding events was similar between the CR and incomplete revascularization groups in both groups with HBR (10.7% versus 10.0%, adjusted HR, 1.07 [95% CI, 0.84\u20131.37],\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.572) and without HBR (4.2% versus 5.0%, adjusted HR, 0.98 [95% CI, 0.78\u20131.23],\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.867).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In patients with acute myocardial infarction and multivessel disease, CR was associated with a lower risk of major adverse cardiac and cerebrovascular events compared with incomplete revascularization in both HBR and non\u2010HBR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p xml:lang=\"en\">KAMIR\u2010NIH; KCT\u20100000863, KAMIR\u2010V; KCT\u20100008355.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.042507","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:22:09Z","timestamp":1783074129000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes of Complete Revascularization in Acute Myocardial Infarction Patients With High Bleeding Risk and Multivessel Disease"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3833-3789","authenticated-orcid":false,"given":"Onyou","family":"Kim","sequence":"first","affiliation":[{"name":"Sungkyunkwan University School of Medicine","place":["Seoul, Korea"]},{"name":"Korea University Anam Hospital","place":["Seoul, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2020-7028","authenticated-orcid":false,"given":"Hyun Sung","family":"Joh","sequence":"additional","affiliation":[{"name":"Seoul National University Boramae Medical Center, Seoul National University College of Medicine","place":["Seoul, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4554-041X","authenticated-orcid":false,"given":"Hyun Kuk","family":"Kim","sequence":"additional","affiliation":[{"name":"University of Chosun College of Medicine","place":["Gwangju, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3186-0770","authenticated-orcid":false,"given":"Ju Han","family":"Kim","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital, Chonnam National University Medical School","place":["Gwangju, South Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0192-8161","authenticated-orcid":false,"given":"Young Joon","family":"Hong","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital, Chonnam National University Medical School","place":["Gwangju, South Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2022-9366","authenticated-orcid":false,"given":"Youngkeun","family":"Ahn","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital, Chonnam National University Medical School","place":["Gwangju, South Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2424-810X","authenticated-orcid":false,"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital, Chonnam National University Medical School","place":["Gwangju, South Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-1915","authenticated-orcid":false,"given":"Seung Ho","family":"Hur","sequence":"additional","affiliation":[{"name":"Keimyung University Dongsan Medical Center","place":["Daegu, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3453-0427","authenticated-orcid":false,"given":"Doo\u2010Il","family":"Kim","sequence":"additional","affiliation":[{"name":"Inje University College of Medicine","place":["Busan, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3456-8705","authenticated-orcid":false,"given":"Kiyuk","family":"Chang","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea","place":["Seoul, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hun Sik","family":"Park","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1362-9804","authenticated-orcid":false,"given":"Jang\u2010Whan","family":"Bae","sequence":"additional","affiliation":[{"name":"Good Samsun Hospital","place":["Busan, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0763-4754","authenticated-orcid":false,"given":"Jin\u2010Ok","family":"Jeong","sequence":"additional","affiliation":[{"name":"Chungnam National University College of Medicine","place":["Daejeon, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Hwan","family":"Park","sequence":"additional","affiliation":[{"name":"Sungkyunkwan University School of Medicine","place":["Changwon, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4911-8854","authenticated-orcid":false,"given":"Kyeong Ho","family":"Yun","sequence":"additional","affiliation":[{"name":"Wonkwang University Hospital","place":["Iksan, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6305-4442","authenticated-orcid":false,"given":"Chang\u2010Hwan","family":"Yoon","sequence":"additional","affiliation":[{"name":"Seoul National University Bundang Hospital","place":["Seongnam\u2010si, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2458-5544","authenticated-orcid":false,"given":"Yisik","family":"Kim","sequence":"additional","affiliation":[{"name":"Chonbuk National University Hospital and Chonbuk National University Medical School","place":["Jeonju, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Yong","family":"Hwang","sequence":"additional","affiliation":[{"name":"Gyeongsang National University School of Medicine and Gyeongsang National University 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