{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T11:44:47Z","timestamp":1782992687752,"version":"3.54.5"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Heart transplant (HT) and left ventricular assist devices (LVADs) are treatment options for advanced heart failure refractory to standard therapy. Historically, LVADs have been used as either destination therapy or a bridge to transplant. However, recent changes to the organ allocation system have deprioritized patients on LVADs as transplant recipients, leading to divisive views on the role of an LVAD. The comparative short\u2010term care burden with each modality remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      We aimed to describe and compare characteristics, outcomes, and cost burden during index hospitalizations and 30\u2010day and 90\u2010day readmissions associated with HTs and durable LVADs from a large, national administrative database. A review of the Nationwide Readmissions Database from 2018 to 2021 describing a cohort identified using\n                      <jats:italic toggle=\"no\">International Classification of Diseases, Tenth Revision, Clinical Modification<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"no\">ICD\u201010\u2010CM<\/jats:italic>\n                      ) procedure codes: 02YA0Z0 and 02HA0QZ.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">We identified 27\u2009308 index hospital admissions; 52.4% received LVADs, and the remainder received HTs. Compared with HT recipients, LVAD recipients were older and more likely male, of lower socioeconomic status, had longer index hospital stays, and had more expensive index hospitalizations. A higher proportion of LVAD recipients required rehospitalization in 30\u2009days. The most frequent causes of rehospitalization in the LVAD group at both 30 and 90\u2009days were heart failure, device complications, and gastrointestinal bleeding. The most frequent causes in the HT group at 30 and 90\u2009days were transplant complications, renal dysfunction, and sepsis (at 90\u2009days only). Thirty\u2010 and 90\u2010day rehospitalization costs were greater in the HT group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Both LVAD and HT had comparable burdens on resources and short\u2010term rehospitalization risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.043588","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T11:11:47Z","timestamp":1771931507000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Short\u2010Term Care Burden After Left Ventricular Assist Device Implantation and Heart Transplant in the United States"],"prefix":"10.1161","volume":"15","author":[{"given":"Balaphanidhar","family":"Mogga","sequence":"first","affiliation":[{"name":"Frank H Netter School of Medicine\/Quinnipiac University","place":["Bridgeport, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0543-2235","authenticated-orcid":false,"given":"Ashwin","family":"Pillai","sequence":"additional","affiliation":[{"name":"University of Connecticut John Dempsey Hospital","place":["Farmington, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0928-3866","authenticated-orcid":false,"given":"Karanrajsinh","family":"Raol","sequence":"additional","affiliation":[{"name":"Frank H Netter School of Medicine\/Quinnipiac University","place":["Bridgeport, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2172-0931","authenticated-orcid":false,"given":"William L.","family":"Baker","sequence":"additional","affiliation":[{"name":"Hartford HealthCare Heart and Vascular Institute","place":["Hartford, USA"]},{"name":"University of Connecticut School of Pharmacy","place":["Storrs, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7754-9953","authenticated-orcid":false,"given":"David A.","family":"Baran","sequence":"additional","affiliation":[{"name":"Advanced Heart Failure Program","place":["Weston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prathyusha","family":"Muddluru","sequence":"additional","affiliation":[{"name":"University of Louisville","place":["Louisville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeina","family":"Jedeon","sequence":"additional","affiliation":[{"name":"Hartford HealthCare Heart and Vascular Institute","place":["Hartford, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6662-1645","authenticated-orcid":false,"given":"Sreenivas","family":"Sagili","sequence":"additional","affiliation":[{"name":"Rochester Institute of Technology","place":["Rochester, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2324-3614","authenticated-orcid":false,"given":"Abhishek","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Hartford HealthCare Heart and Vascular Institute","place":["Hartford, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1900486"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.16197"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2023.01.009"},{"key":"e_1_3_2_5_2","volume-title":"Healthcare Cost and Utilization Project (HCUP)","author":"NRD Overview","year":"2024","unstructured":"NRD Overview . 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Accessed February 8 2025. https:\/\/news.medtronic.com\/2021\u201006\u201003\u2010Medtronic\u2010to\u2010Stop\u2010Distribution\u2010and\u2010Sale\u2010of\u2010HVAD\u2010TM\u2010System."},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11072022"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.125.043588","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T11:08:03Z","timestamp":1782990483000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.125.043588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,3]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,3,3]]}},"alternative-id":["10.1161\/JAHA.125.043588"],"URL":"https:\/\/doi.org\/10.1161\/jaha.125.043588","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,3]]},"assertion":[{"value":"2025-05-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e043588"}}