{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:36:28Z","timestamp":1791905788048,"version":"4.3.4"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,10,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The diagnostic performance of automated office blood pressure (AOBP) in screening for hypertension in people with HIV (PWH) is not known.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">We conducted a cross\u2010sectional analysis of baseline data from PWH and people without HIV (PWoH) from the Mwanza HIV&amp;CVD cohort study. We conducted unattended AOBP and 24\u2010hour ambulatory BP monitoring as recommended by international guidelines. Using average 24\u2010hour BP as the reference standard, we estimated the prevalence of hypertensive diagnostic phenotypes and calculated measures of diagnostic performance at different diagnostic cutoffs in participants.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We included 959 participants (50.4% PWH and 49.6% PWoH). Characteristics were similar across participant groups. The median age was 44\u2009years (interquartile range, 38\u201350\u2009years), and 69.8% were women. Overall prevalence of hypertension, based on average 24\u2010hour ambulatory BP monitoring, was 35.3% using European Society of Hypertension cutoffs and did not differ by HIV infection status. Masked hypertension was present in 25.7% (95% CI, 22.0%\u201329.8%) of PWH and 26.7% (95% CI, 22.9%\u201330.8%) of PWoH. The sensitivity of unattended AOBP was 25.7% for PWH (95% CI, 19.3%\u201333.1%) and 25.7% for PWoH (95% CI, 19.4%\u201333.0%) with little difference in the area under the receiver\u2010operating curve by HIV infection status. Based on 24\u2010hour BP averages, 24.2% of PWH and 21.6% of PWoH had isolated nocturnal hypertension.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">More than half of individuals with hypertension on ambulatory BP monitoring, irrespective of their HIV infection status, may be misdiagnosed if unattended AOBP alone is used to screen for hypertension in sub\u2010Saharan Africa.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.125.043957","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T11:16:31Z","timestamp":1758280591000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic Performance of Unattended Automated Office Blood Pressure Measurement for Hypertension Screening Among People With and Without HIV"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6926-8556","authenticated-orcid":false,"given":"Ruth K.","family":"Lucinde","sequence":"first","affiliation":[{"name":"KEMRI\u2010Wellcome Trust Research Programme","place":["Kilifi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Willkens","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benson","family":"Issarow","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salama","family":"Fadhil","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody","family":"Cichowitz","sequence":"additional","affiliation":[{"name":"University of California San Francisco","place":["San Francisco, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Ayieko","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Godfrey","family":"Kisigo","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]},{"name":"London School of Hygiene and Tropical Medicine","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Venkatraman","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9960-7280","authenticated-orcid":false,"given":"Heiner","family":"Grosskurth","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]},{"name":"London School of Hygiene and Tropical Medicine","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9458-0111","authenticated-orcid":false,"given":"Ana C.","family":"Krieger","sequence":"additional","affiliation":[{"name":"Neurology and Genetic Medicine, Weill Cornell Medical College","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard B.","family":"Devereux","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9286-6930","authenticated-orcid":false,"given":"Myung Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1753-4060","authenticated-orcid":false,"given":"Saidi","family":"Kapiga","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]},{"name":"London School of Hygiene and Tropical Medicine","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N.","family":"Peck","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine","place":["New York, USA"]},{"name":"Mwanza Intervention Trials Unit, National Institute of Medical Research","place":["Mwanza, Tanzania"]},{"name":"Catholic University of Health and Allied Sciences","place":["Mwanza, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1267-6422","authenticated-orcid":false,"given":"Anthony O.","family":"Etyang","sequence":"additional","affiliation":[{"name":"KEMRI\u2010Wellcome Trust Research Programme","place":["Kilifi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-16662-z"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-019-0244-2"},{"key":"e_1_3_2_4_2","volume-title":"Global Report on Hypertension: the Race against a Silent Killer","author":"World Health Organization","year":"2023","unstructured":"World Health Organization . Global Report on Hypertension: the Race against a Silent Killer. Geneva: World Health Organization; 2023."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(21)01330-1"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.121.18884"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.117.033369"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.10893"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.122.19889"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.10850"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.5830\/CVJA-2020-055"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-024-00913-6"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/2047487318823575"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/jch.14300"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-021-02074-7"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000087"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2021.01.070"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0148920"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01573-8"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-014-0125-2"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-015-0177-z"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000066"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000003480"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae178"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.15026"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.111.00217"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDra2300232"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91748-9"},{"key":"e_1_3_2_29_2","volume-title":"HEARTS: technical package for cardiovascular disease management in primary health care: risk\u2010based CVD management. In: Hearts: technical package for cardiovascular disease management in primary health care: risk\u2010based CVD management","author":"Organization WH","year":"2020","unstructured":"Organization WH . HEARTS: technical package for cardiovascular disease management in primary health care: risk\u2010based CVD management. In: Hearts: technical package for cardiovascular disease management in primary health care: risk\u2010based CVD management. Geneva; 2020."},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.5334\/gh.1206"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10479"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000001874"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.119.13574"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0000000000001868"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2019.08.006"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1097\/hjh.0b013e3282fbcedf"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpad102"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/jch.13321"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.5334\/gh.945"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.118.12740"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-75892-y"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.125.043957","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T09:33:21Z","timestamp":1759916001000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.125.043957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,7]]},"references-count":40,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2025,10,7]]}},"alternative-id":["10.1161\/JAHA.125.043957"],"URL":"https:\/\/doi.org\/10.1161\/jaha.125.043957","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,7]]},"assertion":[{"value":"2025-06-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e043957"}}