{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T15:24:22Z","timestamp":1766157862684,"version":"3.48.0"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"24","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2025,12,16]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Over 315 million adults live with hypertension in India, of whom only 37% are diagnosed. In addition to community\u2010based screening, targeting high\u2010risk households may identify undiagnosed individuals. We estimated the magnitude of household aggregation of diagnosed and undiagnosed hypertension among co\u2010residing adults and evaluated whether household members offer pathways for novel screening and management strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">The overall sample consisted of 450\u2009520 households with 1\u2009407\u2009886 adult participants (18\u201399\u2009years old) of the Indian National Family Health Survey\u20105, 2019 to 2021. Household aggregation was defined as \u22652 co\u2010residing members of a household having hypertension (self\u2010reported as physician diagnosed, or measured systolic blood pressure\u2009\u2265140, or diastolic blood pressure \u226590\u2009mm Hg). Among the analytic sample (mean age, 32.5\u2009years; 53.2% women), 25.8% had hypertension, and 48.4% of respondents had \u22651 other members in the household with hypertension. Individuals with diagnosed (prevalence ratio [PR], 2.49 [95% CI, 2.44\u20132.54]) and undiagnosed hypertension (PR, 1.16 [95% CI, 1.15\u20131.17]) were more likely to cluster with others of the same status. Exploratory analyses suggest that the number of households to be screened to identify 1 new case of undiagnosed hypertension was lowest for households with a newly detected (ie, previously undiagnosed) individual with hypertension, followed by households of individuals with normal blood pressure and diagnosed hypertension, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Our study provides novel evidence about aggregation of hypertension among Indian households. Given the high burden of hypertension in India, household\u2010focused screening and management interventions can augment current strategies for closing the gaps in hypertension diagnosis and control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.044340","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T11:02:17Z","timestamp":1765450937000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Household Aggregation of Hypertension in India: A Cross\u2010Sectional Study of Nationally Representative Data From 450 000 Households"],"prefix":"10.1161","volume":"14","author":[{"given":"Krishna Om","family":"Sanaka","sequence":"first","affiliation":[{"name":"Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7014-0576","authenticated-orcid":false,"given":"Erica L.","family":"Kocher","sequence":"additional","affiliation":[{"name":"Emory University","place":["Atlanta, USA"]},{"name":"Emory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil Srinivasapura","family":"Venkateshmurthy","sequence":"additional","affiliation":[{"name":"Center for Chronic Disease Control","place":["New Delhi, India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil","family":"Tandon","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences","place":["New Delhi, India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0082-5857","authenticated-orcid":false,"given":"Shivani A.","family":"Patel","sequence":"additional","affiliation":[{"name":"Emory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University","place":["Atlanta, USA"]},{"name":"Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7266-2503","authenticated-orcid":false,"given":"Mohammed K.","family":"Ali","sequence":"additional","affiliation":[{"name":"Emory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University","place":["Atlanta, USA"]},{"name":"Emory University","place":["Atlanta, USA"]},{"name":"Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3825-9897","authenticated-orcid":false,"given":"Jithin Sam","family":"Varghese","sequence":"additional","affiliation":[{"name":"Emory Global Diabetes Research Center of the Woodruff Health Sciences Center and Emory University","place":["Atlanta, USA"]},{"name":"Emory University","place":["Atlanta, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(23)00119-5"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.39098"},{"key":"e_1_3_2_4_2","unstructured":"Ministry of Health & Family Welfare Government of India . 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