{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T11:45:33Z","timestamp":1782992733643,"version":"3.54.5"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,3,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Intravascular ultrasound (IVUS)\u2010guided percutaneous coronary intervention improves patient outcomes, yet the impact of a center's IVUS experience on long\u2010term outcomes remains unclear. We evaluated whether the prognostic association of IVUS\u2010guided percutaneous coronary intervention in patients with acute myocardial infarction differs based on a center's level of IVUS use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We retrospectively analyzed 9752 patients with acute myocardial infarction treated with second\u2010generation drug\u2010eluting stents from the KAMIR\u2010NIH (Korean Acute Myocardial Infarction Registry\u2013National Institutes of Health). The primary outcome was 3\u2010year major adverse cardiovascular events, defined as a composite of all\u2010cause death, myocardial infarction, and coronary revascularization. The secondary outcome was target\u2010lesion failure, defined as a composite of cardiac death, target\u2010vessel myocardial infarction, and ischemia\u2010driven target lesion revascularization. Centers were classified into higher\u2010 or lower\u2010IVUS\u2010use groups on the basis of median institutional usage (10.3%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      In higher\u2010use centers, IVUS\u2010guided percutaneous coronary intervention was associated with lower rates of major adverse cardiovascular events (15.3% versus 18.5%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.016) and target\u2010lesion failure (6.3% versus 8.3%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.039) in propensity score\u2013matched populations. Multivariate Cox analysis confirmed lower risks of major adverse cardiovascular events (hazard ratio [HR], 0.80 [95% CI, 0.69\u20130.93];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.003) and target\u2010lesion failure (HR, 0.75 [95% CI, 0.59\u20130.93];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.01). Conversely, in lower\u2010use centers, IVUS guidance was not associated with significant differences in major adverse cardiovascular events (15.7% versus 18.6%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.422) or target\u2010lesion failure (8.9% versus 10.4%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.644).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">The association of IVUS\u2010guided percutaneous coronary intervention with lower adverse event rates was more apparent and statistically demonstrable in centers with higher IVUS use. These findings suggest that institutional experience may amplify the observable impact of IVUS guidance, underscoring the potential value of standardized IVUS implementation in acute myocardial infarction management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.045151","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T10:23:26Z","timestamp":1772187806000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Clinical Outcomes of Acute Myocardial Infarction Based on Institutional Experience With IVUS"],"prefix":"10.1161","volume":"15","author":[{"given":"Youngjoon","family":"Kwon","sequence":"first","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8457-0403","authenticated-orcid":false,"given":"Namkyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3703-9796","authenticated-orcid":false,"given":"Do\u2010Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Eulji University School of Medicine","place":["Daejeon, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8780-5260","authenticated-orcid":false,"given":"Byungwon","family":"Kim","sequence":"additional","affiliation":[{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8594-5983","authenticated-orcid":false,"given":"Jong Sung","family":"Park","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon Jung","family":"Park","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5245-9863","authenticated-orcid":false,"given":"Bo Eun","family":"Park","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9903-1848","authenticated-orcid":false,"given":"Hong Nyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7101-0236","authenticated-orcid":false,"given":"Jang Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1646-6126","authenticated-orcid":false,"given":"Dong Heon","family":"Yang","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hun Sik","family":"Park","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9455-0190","authenticated-orcid":false,"given":"Yongkeun","family":"Cho","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital","place":["Daegu, Republic of Korea"]},{"name":"Kyungpook National University","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang Soo","family":"Cha","sequence":"additional","affiliation":[{"name":"Pusan National University Hospital","place":["Busan, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-1915","authenticated-orcid":false,"given":"Seung\u2010Ho","family":"Hur","sequence":"additional","affiliation":[{"name":"Keimyung University Dongsan Medical Center, Cardiovascular Medicine","place":["Daegu, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6632-7239","authenticated-orcid":false,"given":"Jin\u2010Yong","family":"Hwang","sequence":"additional","affiliation":[{"name":"Gyeongsang National University School of Medicine, Gyeongsang National University Hospital","place":["Jinju, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2424-810X","authenticated-orcid":false,"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital","place":["Gwangju, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the KAMIR\u2010NIH 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