{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:21:48Z","timestamp":1788348108784,"version":"build-2803163510"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,2,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      The effectiveness and safety of endovascular treatment (\n                      <jats:styled-content style=\"fixed-case\" toggle=\"no\">EVT<\/jats:styled-content>\n                      ) compared with standard medical treatment (\n                      <jats:styled-content style=\"fixed-case\" toggle=\"no\">SMT<\/jats:styled-content>\n                      ) for acute basilar artery occlusion in patients with National Institutes of Health Stroke Scale (\n                      <jats:styled-content style=\"fixed-case\" toggle=\"no\">NIHSS<\/jats:styled-content>\n                      ) scores \u226410 remain unclear. This study aimed to investigate the effectiveness and safety of\n                      <jats:styled-content style=\"fixed-case\" toggle=\"no\">EVT<\/jats:styled-content>\n                      versus\n                      <jats:styled-content style=\"fixed-case\" toggle=\"no\">SMT<\/jats:styled-content>\n                      in patients with acute basilar artery occlusion with\n                      <jats:styled-content style=\"fixed-case\" toggle=\"no\">NIHSS<\/jats:styled-content>\n                      scores \u226410.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients with acute basilar artery occlusion and NIHSS scores \u226410 included in this study were derived from a nationwide prospective registry in China. Patients were divided into the EVT and SMT groups. The primary outcome was the distribution of modified Rankin Scale score at 90\u2009days. Safety outcomes included death at 90\u2009days and symptomatic intracerebral hemorrhage within 48\u2009hours.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">Among 106 patients, 78 (73.6%) received EVT. The median age was 64 (interquartile range, 59\u201371) years, and 23 (21.7%) were women. Compared with SMT, EVT was associated with a favorable shift in the distribution of modified Rankin Scale score at 90\u2009days (adjusted odds ratio, 6.22 [95% CI, 2.31\u201316.73]) and lower 90\u2010day death (adjusted odds ratio, 0.23 [95% CI, 0.06\u20130.88]). There was no significant difference in the incidence of symptomatic intracerebral hemorrhage within 48\u2009hours between the 2 groups. At 1\u2010year follow\u2010up, functional outcomes continued to favor EVT over SMT. In both groups, as the baseline NIHSS score increased, the probability of achieving favorable outcomes progressively decreased, while the probability of death increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In patients with acute basilar artery occlusion and NIHSS scores of \u226410, EVT was associated with better functional outcomes and lower mortality rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.045428","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T10:59:42Z","timestamp":1770807582000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of Endovascular Treatment for Acute Basilar Artery Occlusion With National Institutes of Health Stroke Scale Score 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