{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T13:53:43Z","timestamp":1781790823259,"version":"3.54.5"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,6,2]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Suboptimal stent deployment detected by optical coherence tomography (OCT) correlates with adverse outcomes, yet its long\u2010term prognosis and associations with lesion characteristics in patients with acute myocardial infarction (MI) receiving drug\u2010eluting stents remain unclear. This study aimed to investigate the impact of OCT\u2010defined stent parameters on long\u2010term outcomes and identify lesion features predictive of suboptimal stent deployment in patients with acute MI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Between January 2018 and December 2020, patients with acute MI undergoing successful intervention with drug\u2010eluting stents and postprocedural OCT imaging at the target lesions were included. The end point was device\u2010oriented cardiovascular events, a composite of cardiac death, target\u2010vessel related MI, and target\u2010lesion revascularization. Suboptimal OCT stent deployment was defined as the presence of \u22651 OCT findings significantly associated with device\u2010oriented cardiovascular events. In a subgroup with preprocedural OCT imaging for target lesions, lesion morphology was assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Among 881 patients (906 lesions with final OCT imaging), minimum stent area&lt;4.5\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      , irregular protrusion, and distal reference lumen narrowing were independent predictors of device failure, at a median follow\u2010up of 4.0\u2009years. Patients with suboptimal OCT stent deployment had a higher incidence of device\u2010oriented cardiovascular events, which was primarily driven by cardiac death and target lesion revascularization. In the subgroup (including 789 lesions), multivariate analysis identified plaque rupture, cholesterol crystals, and smaller reference lumen area as predictors of suboptimal OCT stent deployment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Suboptimal stent deployment, defined by specific quantitative OCT criteria, was associated with device failure at long\u2010term follow\u2010up in patients with acute MI successfully treated with drug\u2010eluting stents. Specific OCT\u2010identified lesion characteristics were associated with suboptimal OCT stent deployment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.045609","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T10:49:02Z","timestamp":1779706142000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Impact and Lesion Characteristics of Suboptimal Optical Coherence Tomography Stent Deployment in Patients With Acute Myocardial Infarction"],"prefix":"10.1161","volume":"15","author":[{"given":"Jiawei","family":"Zhao","sequence":"first","affiliation":[{"name":"The 2nd Affiliated Hospital of Harbin Medical University","place":["Harbin, China"]},{"name":"Chinese Ministry of Education","place":["Harbin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhao","sequence":"additional","affiliation":[{"name":"The 2nd Affiliated 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