{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T05:21:19Z","timestamp":1787721679016,"version":"build-2784847793"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,7,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Atrial fibrillation (AF) is the most common arrhythmia, affecting up to 6\u2009million in the United States, and is associated with significant morbidity and mortality. Despite higher rates of AF clinical and social risk factors, underrepresented racial and ethnic group individuals have lower AF incidence. Structural factors, such as neighborhood\u2010level racial and ethnic residential segregation, have been associated with incident cardiometabolic disease, particularly among underrepresented individuals. However, as data on segregation and incident AF are sparse our objective was to examine the association of segregation on AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Data from MESA (Multi\u2010Ethnic Study of Atherosclerosis; baseline 2000\u20132002) were used to identify those with a diagnosis of AF during follow\u2010up. Own\u2010group racial and ethnic segregation was defined by local Gi* statistic, which compares the percentage of each racial and ethnic group in a current census tract to the surrounding area. Racial\u2010 and ethnic\u2010stratified Cox proportional hazard models were used to estimate hazard ratios comparing across segregation levels. Models were adjusted for demographic, participant, and neighborhood level socioeconomic, and clinical factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">Our cohort comprised 5375 participants (31% Black, 25% Hispanic\/Latino, 44% White). During a median follow\u2010up of 16.6\u2009years, 1035 participants (19.3%) were diagnosed with AF. Black and Hispanic\/Latino participants had the highest prevalence of AF risk factors at baseline and were more likely to reside in segregated neighborhoods than White participants. After adjusting for demographic, socioeconomic, and clinical factors, neighborhood segregation was not found to be associated with AF across racial and ethnic groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this longitudinal analysis we did not observe an association between residential segregation and AF incidence for Black, Hispanic\/Latino, or White participants in fully adjusted models. Further research is needed to understand how individual factors may intersect with clinical, health care, and structural factors to drive previously described differential risk of AF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.045942","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:37:57Z","timestamp":1782211077000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Neighborhood\u2010Level Racial and Ethnic Residential Segregation and Incidence of Atrial Fibrillation: The Multi\u2010Ethnic Study of Atherosclerosis"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4494-5028","authenticated-orcid":false,"given":"Utibe R.","family":"Essien","sequence":"first","affiliation":[{"name":"David Geffen School of Medicine at the University of California Los Angeles","place":["Los Angeles, 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USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7035-0848","authenticated-orcid":false,"given":"Mercedes R.","family":"Carnethon","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine at Northwestern University","place":["Chicago, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3658-6165","authenticated-orcid":false,"given":"Karol E.","family":"Watson","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at University of California Los Angeles","place":["Los Angeles, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8737-0447","authenticated-orcid":false,"given":"Jasmyn J.","family":"Tang","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at the University of California Los Angeles","place":["Los Angeles, 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