{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T05:20:24Z","timestamp":1787721624750,"version":"build-2784847793"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,7,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Increasing use of cardiac implantable electronic devices (CIEDs) has raised concerns about psychological distress in young adults. We evaluated the risk of incident mental disorders after CIED implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Using the Korean National Health Insurance database, we identified individuals aged 20 to 39\u2009years who underwent health checkups in 2009 to 2012. Those receiving a new CIED within 4\u2009years were included, and controls were selected by 1:5 matching for age, sex, and index year. The primary outcome was a composite of newly diagnosed mental disorders (mood disorders and anxiety\/stress\u2010related\/somatoform disorders), and secondary outcomes were the individual components.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">There were 569 CIED recipients (209 pacemakers, 360 implantable cardioverter\u2010defibrillators) and 2821 matched controls analyzed. Over a median follow\u2010up of 5.3\u2009years, both the pacemaker and implantable cardioverter\u2010defibrillator implantations were associated with a significantly higher risk of the primary outcome compared with no device (hazard ratio [HR], 1.63 [95% CI, 1.20\u20132.21] and HR, 1.80 [95% CI, 1.39\u20132.35], respectively). In head\u2010to\u2010head analyses, the risk of the primary outcome did not differ significantly between implantable cardioverter\u2010defibrillator and pacemaker recipients (adjusted HR, 1.09 [95% CI, 0.75\u20131.59]). Risks of secondary outcomes were also increased in both device groups. CIED recipients had a 1.95\u2010fold higher risk of mental disorders within 2\u2009years postimplantation (95% CI, 1.45\u20132.62), and this elevated risk persisted beyond 2\u2009years (HR, 1.54 [95% CI, 1.13\u20132.11]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Among young individuals, both pacemaker and implantable cardioverter\u2010defibrillator implantations were associated with increased risks of mental disorders, supporting proactive psychological screening and interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.046715","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:33:57Z","timestamp":1782210837000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Mental Disorders After Cardiac Implantable Electronic Device Implantation in Young Individuals"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9296-7345","authenticated-orcid":false,"given":"Young\u2010Hae","family":"Go","sequence":"first","affiliation":[{"name":"Seoul National University College of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Seoul National University Hospital","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1717-6662","authenticated-orcid":false,"given":"Chan Soon","family":"Park","sequence":"additional","affiliation":[{"name":"Asan Medical Center, University of Ulsan College of Medicine","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1022-3553","authenticated-orcid":false,"given":"Bongseong","family":"Kim","sequence":"additional","affiliation":[{"name":"Soongsil University","place":["Seoul, South Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1798-7441","authenticated-orcid":false,"given":"Soongu","family":"Kwak","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Seoul National University Hospital","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae\u2010Min","family":"Rhee","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Seoul National University Hospital Healthcare System Gangnam Center","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7950-2131","authenticated-orcid":false,"given":"Hyung\u2010Kwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Seoul National University Hospital","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong\u2010Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Seoul National University Hospital","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungdo","family":"Han","sequence":"additional","affiliation":[{"name":"Soongsil University","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4037-3955","authenticated-orcid":false,"given":"Heesun","family":"Lee","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Seoul National University Hospital Healthcare System 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