{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:07:55Z","timestamp":1789553275928,"version":"build-2803163510"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,6,16]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">This observational, quality initiative evaluated the impact of changing from a passive (dismissible) to an active (nondismissible without action) electronic health record alert on guideline\u2010recommended lipid\u2010lowering therapy (LLT) prescriptions in patients with recent myocardial infarction at risk for secondary events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We sequentially recruited a retrospective passive\u2010alert (February 2018\u2013July 2019; n=733) and a prospective active\u2010alert (August 2020\u2013January 2022; n=587) cohort of patients who triggered an alert to intensify LLT or order a low\u2010density lipoprotein\u2010cholesterol (LDL\u2010C) test if they had a recent myocardial infarction (within 12\u2009months) and elevated (\u226570\u2009mg\/dL) or missing LDL\u2010C. Prescribed LLTs and cumulative percentages of patients with missing or LDL\u2010C &lt;70 and &lt;55\u2009mg\/dL were assessed in 6\u2010month periods up to 24\u2009months. Reasons for not intensifying LLTs were recorded with the active alert.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">During 24\u2009months, statin and high\u2010intensity statin use increased from 59% to 87% and from 39% to 69%, respectively, in the passive\u2010alert cohort. In the active\u2010alert cohort, statin and high\u2010intensity statin use were high and changed minimally (79% to 80% and 70% to 73%), but ezetimibe and proprotein convertase subtilisin\/kexin type 9 inhibitor use increased from 12% to 35% and from 2% to 8% (odds ratio, 4.69 [95% CI, 3.22\u20136.96] and 4.07 [95% CI, 1.92\u20139.46]), respectively. LDL\u2010C testing and LDL\u2010C goal attainment improved in both cohorts. LDL\u2010C not current (41.7%) was the most common reason for not intensifying LLT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Continued efforts are needed to encourage guideline\u2010directed LLT intensification for patients with a recent myocardial infarction who are at risk of another cardiac event.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.047116","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T11:51:48Z","timestamp":1781005908000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Electronic Health Record Alerts\u00a0to Improve Lipid Lowering After a Recent Myocardial Infarction"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9750-2589","authenticated-orcid":false,"given":"Dean G.","family":"Karalis","sequence":"first","affiliation":[{"name":"Cardiology Consultants of Philadelphia","place":["Philadelphia, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Richter","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital","place":["Philadelphia, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Hessen","sequence":"additional","affiliation":[{"name":"Cardiology Consultants of Philadelphia","place":["Philadelphia, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Moeller","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University","place":["Philadelphia, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laney K.","family":"Jones","sequence":"additional","affiliation":[{"name":"Amgen Inc.","place":["Thousand Oaks, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31357-5"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1410489"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1615664"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1801174"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000625"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz455"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.07.006"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2022.4373"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.123.010335"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2024.2398444"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.25505"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.120.007485"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.02.048"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2023.0228"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.122.009787"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpc.2024.100722"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2024.101231"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.0911"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2019.10.014"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2016.02.016"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpc.2023.100499"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2018.1511"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.1810"}],"container-title":["Journal 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