{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:08:28Z","timestamp":1789013308876,"version":"build-2803163510"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,8,4]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">There are limited data guiding the optimal inflation time for coronary drug\u2010coated balloons. The aim of this study was to assess the clinical efficacy of an inflation time of \u226530\u2009seconds compared with &lt;30\u2009seconds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We conducted an observational nationwide analysis using the SCAAR (Swedish Coronary Angiography and Angioplasty Registry) to identify all patients undergoing percutaneous coronary intervention with drug\u2010coated balloons and their inflation times. Outcomes were assessed at 1\u2009year using Kaplan\u2013Meier estimates and adjusted Cox regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      The &lt;30\u2010second group comprised 412 patients, and the \u226530\u2010second group 10\u2009826 patients. Patients in the &lt;30\u2010second group presented more often with lesions in proximal segments. After a 1\u2010year follow\u2010up, \u226530\u2009seconds was associated with lower rates of target segment revascularization compared with &lt;30\u2009seconds (3.2% versus 6.4%, adjusted hazard ratio [HR], 0.47 [95% CI, 0.32\u20130.69],\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      \u22640.001) and target vessel myocardial infarction (1.8% versus 5.3%, adjusted HR, 0.32 [95% CI, 0.21\u20130.50],\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      \u22640.001). No difference was observed for all\u2010cause mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this analysis, including 11\u2009238 patients undergoing PCI with drug\u2010coated balloons, \u226530\u2009second inflation time was associated with improved outcomes compared with a shorter inflation time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.047354","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:13:41Z","timestamp":1785496421000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Drug\u2010Coated Balloon Inflation Time on Outcome After Percutaneous Coronary Intervention: An Observational Study From SCAAR"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8398-4221","authenticated-orcid":false,"given":"Sacharias","family":"von Koch","sequence":"first","affiliation":[{"name":"Lund University","place":["Lund, Sweden"]},{"name":"Sk\u00e5ne University Hospital","place":["Lund, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8031-5998","authenticated-orcid":false,"given":"Mikael","family":"Zhou","sequence":"additional","affiliation":[{"name":"Lund University","place":["Lund, Sweden"]},{"name":"Sk\u00e5ne University Hospital","place":["Lund, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5955-5056","authenticated-orcid":false,"given":"Anton","family":"H\u00e5kansson","sequence":"additional","affiliation":[{"name":"Lund University","place":["Lund, Sweden"]},{"name":"Sk\u00e5ne University Hospital","place":["Lund, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9483-5962","authenticated-orcid":false,"given":"Truls","family":"R\u00e5munddal","sequence":"additional","affiliation":[{"name":"Sahlgrenska University Hospital","place":["Gothenburg, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3875-8621","authenticated-orcid":false,"given":"Elmir","family":"Omerovic","sequence":"additional","affiliation":[{"name":"Sahlgrenska University Hospital","place":["Gothenburg, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4638-4014","authenticated-orcid":false,"given":"Sammy","family":"Zwackman","sequence":"additional","affiliation":[{"name":"Link\u00f6ping University","place":["Link\u00f6ping, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3042-5766","authenticated-orcid":false,"given":"David","family":"Erlinge","sequence":"additional","affiliation":[{"name":"Lund University","place":["Lund, Sweden"]},{"name":"Sk\u00e5ne University Hospital","place":["Lund, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1914-2282","authenticated-orcid":false,"given":"Tuomas T.","family":"Rissanen","sequence":"additional","affiliation":[{"name":"North Karelia Central Hospital, Siunsote","place":["Joensuu, Finland"]},{"name":"University of Eastern Finland","place":["Kuopio, Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4242-9801","authenticated-orcid":false,"given":"Moman A.","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Lund University","place":["Lund, Sweden"]},{"name":"Sk\u00e5ne University Hospital","place":["Lund, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","unstructured":"SWEDEHEART Annual report 2024. 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