{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:08:46Z","timestamp":1789013326967,"version":"build-2803163510"},"reference-count":124,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,8,4]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Among arrhythmias observed in SARS\u2010CoV\u20102 infection, bradyarrhythmia poses the dilemma of urgent pacing. In this population, data on patients' characteristics and clinical outcomes are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">A systematic literature search was conducted for bradyarrhythmia associated with COVID\u201019 from inception to December 2024 following Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses Extension for Scoping Reviews guidelines; quality assessment was performed using the Joanna Briggs Institute critical appraisal tool. From each report, the type of bradyarrhythmia, relevant clinical variables, and outcomes were extracted. Comparison between groups with different bradyarrhythmias was performed for the variables available in all cases. Cluster analyses were performed using both the k\u2010means and hierarchical methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Overall, 103 case series\/case reports were identified reporting data on 151 patients: 76 with sinus node dysfunction and 75 with atrioventricular block (AVB). Median age was 54.5\u2009years; 10.6% were pediatric patients. Despite few comorbidities, 24.5% required mechanical ventilation and 11.3% died. Sinus node dysfunction was more frequently associated with antiviral therapy, while patients with permanent AVB were significantly older (58 versus 48.5\u2009years;\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.011) and showed a significant trend toward a higher mortality rate (23.1% versus 5.6%;\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.048) than those with transient AVB. Cluster analyses showed a higher inflammatory profile in younger patients associated with left ventricular dysfunction and AVB.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">COVID\u201019 can be associated with sinus node dysfunction or AVB even in a young patient population exhibiting a high inflammatory profile. The need for mechanical ventilation and the mortality rate was not negligible. Sinus node dysfunction was associated with the use of antiviral therapy, and permanent AVB was associated with a higher mortality rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.047934","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T10:26:02Z","timestamp":1784975162000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Bradyarrhythmia in Hospitalized Patients With SARS\u2010CoV\u20102 Infection: A Systematic Scoping Review and Clustering Analyses"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5924-9036","authenticated-orcid":false,"given":"Federico","family":"Blasi","sequence":"first","affiliation":[{"name":"University of Insubria","place":["Varese, Italy"]},{"name":"Ospedale di Circolo, ASST\u2010Rhodense","place":["Rho, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5863-4853","authenticated-orcid":false,"given":"Margherita","family":"Casiraghi","sequence":"additional","affiliation":[{"name":"University of Insubria","place":["Varese, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4848-523X","authenticated-orcid":false,"given":"Matteo","family":"Morello","sequence":"additional","affiliation":[{"name":"University of Virginia","place":["Charlottesville, USA"]},{"name":"University of Brescia","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2774-5543","authenticated-orcid":false,"given":"Carlo","family":"Arn\u00f2","sequence":"additional","affiliation":[{"name":"University of Insubria","place":["Varese, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0141-0127","authenticated-orcid":false,"given":"Michele","family":"Golino","sequence":"additional","affiliation":[{"name":"University of Virginia","place":["Charlottesville, USA"]},{"name":"University of Florida College of Medicine\u2014Jacksonville","place":["USA"]},{"name":"Virginia Commonwealth University","place":["Richmond, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5353-4717","authenticated-orcid":false,"given":"Elisa","family":"Franceschi","sequence":"additional","affiliation":[{"name":"Ospedale G. Salvini, ASST\u2010Rhodense","place":["Garbagnate Milanese, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0430-2714","authenticated-orcid":false,"given":"Gianfranco","family":"Alicandro","sequence":"additional","affiliation":[{"name":"University of Milan","place":["Italy"]},{"name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","place":["Milan, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9334-4555","authenticated-orcid":false,"given":"Marco","family":"Vicenzi","sequence":"additional","affiliation":[{"name":"University of Milan","place":["Italy"]},{"name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","place":["Milan, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3278-1721","authenticated-orcid":false,"given":"Roberto","family":"De Ponti","sequence":"additional","affiliation":[{"name":"University of Insubria","place":["Varese, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-020-02487-w"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa508"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa409"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-020-00789-9"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.08.002"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13806"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13237259"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.10.020"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14466"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2020.03.016"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2020.07.015"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2020.09.003"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.8599"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytaa248"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa307"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s42399-020-00497-5"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14042"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2020.05.067"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2020.08.015"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2020.05.023"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2020.06.014"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1716717"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.10461"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2020.08.025"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.11132"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ipej.2020.08.004"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2020.08.006"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2020.07.015"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2020.04.026"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.008719"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytaa323"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1714\/3405.33891"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytaa132"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8833660"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-02933-3"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytaa171"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-1509"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.24969\/hvt.2020.198"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.20-271"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytaa238"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2020.03.028"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2021.e01254"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.6237-20"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.4103\/2221-6189.330747"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14313"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1177\/23247096211013185"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-021-06143-2"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.07.068"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd8020018"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14321"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6124898"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-245289"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piab029"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytab405"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa333"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.210300"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.visj.2020.100920"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.repce.2021.11.018"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14308"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5011294"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(21)04333-3"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-242058"},{"key":"e_1_3_2_64_2","first-page":"164","article-title":"Heart block in coronavirus 2019: a case report","volume":"15","author":"Heidari\u2010Bakavoli A","year":"2021","unstructured":"Heidari\u2010Bakavoli A, Banihashem Rad SH. Heart block in coronavirus 2019: a case report. Int Cardiovasc Res J. 2021;15:164\u2013167.","journal-title":"Int Cardiovasc Res J"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1007\/s42399-020-00712-3"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2021.05.004"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.3892\/mi.2021.24"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1080\/23744235.2021.1903549"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.4268"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.19919"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.4103\/apc.apc_96_21"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000726320.10578.8c"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1080\/10903127.2021.1924325"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-021-03940-4"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.3390\/clinpract11020047"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytab200"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2021.102828"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2020.07.015"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951121004248"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(21)03393-3"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(21)03385-4"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.33963\/KP.a2021.0117"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9955466"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2022.03.429"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytab524"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8807957"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-022-01854-3"},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.27307"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2021.12.020"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.12890\/2022_003026"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.146.suppl_1.14249"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/9371818"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2022.08.1675"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.4103\/ACCJ.ACCJ_12_22"},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.24953\/turkjped.2022.236"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(22)03338-1"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(22)03367-8"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.22926"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(22)03300-9"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(22)03521-5"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.1159\/000519907"},{"key":"e_1_3_2_102_2","first-page":"103","article-title":"Severe symptomatic bradycardia associated with remdesivir use in a covid\u201019 patient: a case report and review of literature","volume":"27","author":"Wani AA","year":"2022","unstructured":"Wani AA, Bhat I, Shafi A, Riaz I. Severe symptomatic bradycardia associated with remdesivir use in a covid\u201019 patient: a case report and review of literature. JK Pract. 2022;27:103\u2013106.","journal-title":"JK Pract"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.14744\/etd.2022.75272"},{"key":"e_1_3_2_104_2","first-page":"108","article-title":"Complete atrioventricular block in COVID\u201019\u2013related myocarditis: a case report","volume":"24","author":"Amir M","year":"2023","unstructured":"Amir M. Complete atrioventricular block in COVID\u201019\u2013related myocarditis: a case report. Iran Heart J. 2023;24:108\u2013113.","journal-title":"Iran Heart J"},{"key":"e_1_3_2_105_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-023-08226-z"},{"key":"e_1_3_2_106_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.3324-23"},{"key":"e_1_3_2_107_2","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X231168304"},{"key":"e_1_3_2_108_2","first-page":"278","article-title":"First reported case of COVID\u201019 induced permanent third\u2010degree atrioventricular (AV) block in a young patient","volume":"13","author":"Hickcox L","year":"2023","unstructured":"Hickcox L, Smolin MR, Movahed MR. First reported case of COVID\u201019 induced permanent third\u2010degree atrioventricular (AV) block in a young patient. Am J Cardiovasc Dis. 2023;13:278\u2013282.","journal-title":"Am J Cardiovasc Dis"},{"key":"e_1_3_2_109_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(23)03693-8"},{"key":"e_1_3_2_110_2","doi-asserted-by":"publisher","DOI":"10.5603\/CJ.2023.0020"},{"key":"e_1_3_2_111_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.6819"},{"key":"e_1_3_2_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihjccr.2023.11.001"},{"key":"e_1_3_2_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2024.03.892"},{"key":"e_1_3_2_114_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.9052"},{"key":"e_1_3_2_115_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2024.06.28"},{"key":"e_1_3_2_116_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.5394"},{"key":"e_1_3_2_117_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2021.02.012"},{"key":"e_1_3_2_118_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.121.320518"},{"key":"e_1_3_2_119_2","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed7030043"},{"key":"e_1_3_2_120_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.29018"},{"key":"e_1_3_2_121_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2021.10.006"},{"key":"e_1_3_2_122_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2024.5466"},{"key":"e_1_3_2_123_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-023-01525-9"},{"key":"e_1_3_2_124_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.022095"},{"key":"e_1_3_2_125_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2020.06.015"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.125.047934","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:42:31Z","timestamp":1789011751000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.125.047934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,4]]},"references-count":124,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2026,8,4]]}},"alternative-id":["10.1161\/JAHA.125.047934"],"URL":"https:\/\/doi.org\/10.1161\/jaha.125.047934","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,4]]},"assertion":[{"value":"2025-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e047934"}}