{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:52:59Z","timestamp":1791355979782,"version":"4.3.1"},"reference-count":65,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,10,6]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Obstructive sleep apnea (OSA) is a modifiable risk factor that benefits from timely detection and treatment to improve poststroke outcomes, yet ethnic\u2010specific features and practical screening strategies remain undercharacterized. We evaluated OSA prevalence, its association with neurocognitive function, and screening performance in Chinese patients with acute cerebral infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this prospective cohort, 183 consecutive Han Chinese inpatients with acute cerebral infarction underwent home sleep apnea testing within 2\u2009weeks of onset. Moderate to severe OSA was defined as an apnea\u2013hypopnea index \u226515 events\/h. Neurocognitive function was assessed by Mini\u2010Mental State Examination and National Institutes of Health Stroke Scale. The diagnostic performance of the STOP\u2010Bang questionnaire, including sensitivity, specificity, positive predictive value, and negative predictive value, was evaluated for identifying moderate to severe OSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      OSA prevalence was 79.2%, with 37.7% moderate to severe. Cognitive impairment (Mini\u2010Mental State Examination &lt;23) was less frequent in patients without OSA than patients with OSA (15.8% versus 31.3%\u201340.8%,\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.048). Sex\u2010stratified analyses showed higher cognitive impairment burden in women comparing non\u2010OSA versus mild OSA (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.040), with no parallel association observed in men (all\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.400). STOP\u2010Bang had limited discrimination (area under the receiver operating characteristic curve, 0.72), with high sensitivity (88.4%) but low specificity (39.5%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Chinese patients with acute cerebral infarction have a high OSA burden. Sex\u2010stratified results suggest potential female\u2010specific vulnerability to OSA\u2010related cognitive impairment, warranting larger cohorts. Given limited specificity and triage value of STOP\u2010Bang, objective sleep apnea evaluation should be performed whenever feasible in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.chictr.org.cn\/\">https:\/\/www.chictr.org.cn\/<\/jats:ext-link>\n                      . Identifier: ChiCTR2000038312.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.048199","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:35:42Z","timestamp":1789738542000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Distinctive Features of Obstructive Sleep Apnea in Chinese Patients With Acute Cerebral Infarction: A Prospective Observational Study"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7060-0018","authenticated-orcid":false,"given":"Wei","family":"Guo","sequence":"first","affiliation":[{"name":"Guangzhou Medical University","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]},{"name":"The First Affiliated Hospital of Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]},{"name":"The Affiliated Brain Hospital, 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