{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:05:47Z","timestamp":1789535147787,"version":"build-2803163510"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,9,15]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">To understand which sociodemographic and anatomic groups have benefited from increases in prenatal diagnosis (PND) of congenital heart disease (CHD), we compared factors associated with overall and earlier (\u226422\u2009weeks) PND from 2006 to 2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">A New Zealand population\u2010based cohort study of all major CHD (death or intervention by 1 year) from 20\u2009weeks' gestation. National cardiac, mortality and governmental data sets were linked for case ascertainment and to obtain the type and timing of diagnosis, maternal age, ethnicity, New Zealand Index of Socioeconomic Deprivation quintile, and domicile.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">The relative increase in PND between the first and last 5\u2009years was greatest in critical CHD subtypes (death or intervention &lt;1 month), particularly coarctation (124%), d\u2010transposition (78%) and conotruncal anomalies (71%), and in previously disadvantaged groups including indigenous M\u0101ori (104%), Pacific (53%), New Zealand Index of Socioeconomic Deprivation quintile 5 (most deprived) (79%) and remote domicile (73%). When adjusted for anatomic factors, PND in the first 5\u2009years was associated with ethnicity (Asian, risk ratio [RR] 1.35, 1.05\u20132.1.73; European, RR 1.33, 1.11\u20131.61 versus M\u0101ori), New Zealand Index of Socioeconomic Deprivation quintile 1\u20104 versus 5 (RR 1.27, 1.07\u20131.50) and domicile in major metropolitan areas (RR 1.18, 1.01\u20131.37). These factors were not associated with PND in later years. Earlier PND was associated with ethnicity, New Zealand Index of Socioeconomic Deprivation and domicile in the first 5\u2009years and with ethnicity and time of obstetric booking in the last 5\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">An increase in PND has benefited previously disadvantaged sociodemographic groups and cardiac conditions where a delayed diagnosis is most threatening to life. Persistent associations between earlier PND and sociodemographic factors require further investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.125.048735","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:50:41Z","timestamp":1788965441000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Increasing Overall Rates of Prenatal Diagnosis Benefit Previously Disadvantaged Anatomic and Sociodemographic Subgroups"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6149-2596","authenticated-orcid":false,"given":"Thomas L.","family":"Gentles","sequence":"first","affiliation":[{"name":"Te Toka Tumai Auckland, Health New Zealand \u2013 Te Whatu Ora","place":["Auckland, New Zealand"]},{"name":"University of Auckland","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3211-403X","authenticated-orcid":false,"given":"Simone","family":"Watkins","sequence":"additional","affiliation":[{"name":"University of Auckland","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6662-1358","authenticated-orcid":false,"given":"David","family":"Perry","sequence":"additional","affiliation":[{"name":"Te Toka Tumai Auckland, Health New Zealand \u2013 Te Whatu Ora","place":["Auckland, New Zealand"]},{"name":"Te Toka Tumai Auckland, Health New Zealand \u2013 Te Whatu Ora","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"de Laat","sequence":"additional","affiliation":[{"name":"Te Toka Tumai Auckland, Health New Zealand \u2013 Te Whatu Ora","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9367-1492","authenticated-orcid":false,"given":"Sue","family":"Crengle","sequence":"additional","affiliation":[{"name":"University of Otago","place":["Dunedin, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6424-6577","authenticated-orcid":false,"given":"Frank","family":"Bloomfield","sequence":"additional","affiliation":[{"name":"University of Auckland","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0681-6652","authenticated-orcid":false,"given":"Lynn","family":"Sadler","sequence":"additional","affiliation":[{"name":"Te Toka Tumai Auckland, Health New Zealand \u2013 Te Whatu Ora","place":["Auckland, New Zealand"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.99.7.916"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.08.056"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2018.1510913"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/s1047951117002682"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.15592"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15589"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2022.03.020"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-3949"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2019.1621814"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6409"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6551"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2024.102780"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-023-03095-z"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26030"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.120.053062"},{"key":"e_1_3_2_17_2","volume-title":"Ethnicity Data Protocols for the Health and Disability Sector","author":"Ministry of Health \u2010 Manat\u016b Hauora","year":"2016","unstructured":"Ministry of Health \u2010 Manat\u016b Hauora . 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