{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T14:32:00Z","timestamp":1793802720280,"version":"4.6.1"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,7,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Dysphagia, an increasingly recognized clinical marker of frailty, is prevalent among older adults yet its impact on cardiovascular postprocedural outcomes remains undetermined. This study evaluated the association between dysphagia and adverse outcomes following major cardiac interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Using the TriNetX database (2020\u20132024), we retrospectively identified adults with and without dysphagia who underwent coronary artery bypass graft, implantable cardioverter\u2010defibrillator placement, transcatheter aortic valve replacement, surgical aortic valve replacement, or mitral transcatheter edge\u2010to\u2010edge repair. Cohorts were propensity matched based on demographics and comorbidities; a sensitivity analysis incorporated additional frailty markers. The 90\u2010day and 1\u2010year risks of mortality, stroke, aspiration pneumonia, infectious pneumonia, hypoxemia, intubation, foreign body in respiratory tract, and esophagogastroduodenoscopy were measured. Kaplan\u2013Meier analyses on survival probability were performed. Hazard ratios (HRs) for mortality, and risk ratios for all outcomes with 95% CIs were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Propensity matched cohorts of patients with and without dysphagia (coronary artery bypass graft, n=5152; implantable cardioverter\u2010defibrillator, n=4112; transcatheter aortic valve replacement, n=4066; surgical aortic valve replacement, n=1982; mitral transcatheter edge\u2010to\u2010edge repair, n=710) were well balanced. Dysphagia was associated with significantly increased 90\u2010day mortality following coronary artery bypass graft (HR, 1.321), implantable cardioverter\u2010defibrillator implantation (HR, 1.398), transcatheter aortic valve replacement (HR, 1.736), and surgical aortic valve replacement (HR, 1.341) (all\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.01) but not mitral transcatheter edge\u2010to\u2010edge repair. Dysphagia also increased the 1\u2010year risk of stroke, hypoxemia, infectious pneumonia, and intubation across all procedures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Dysphagia is associated with increased short\u2010term morbidity and mortality following common cardiovascular procedures. Incorporating dysphagia screening into perioperative workflows may improve patient selection and resource allocation, supporting its inclusion in guideline\u2010directed risk assessment and perioperative optimization pathways.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.126.049122","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:32:13Z","timestamp":1782210733000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Dysphagia: A Novel Risk Factor for Poor Outcomes Following Cardiovascular Procedures"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5703-7453","authenticated-orcid":false,"given":"Anagh","family":"Astavans","sequence":"first","affiliation":[{"name":"The Johns Hopkins University","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3096-177X","authenticated-orcid":false,"given":"Arindam","family":"Bagga","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6827-1602","authenticated-orcid":false,"given":"Anna","family":"Zaeske","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9055-6099","authenticated-orcid":false,"given":"Garrett","family":"Goldin","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]},{"name":"Hackensack Meridian School of Medicine","place":["Nutley, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9941-438X","authenticated-orcid":false,"given":"Ian","family":"Everitt","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel C.","family":"Frank","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0516-9855","authenticated-orcid":false,"given":"Rani K.","family":"Hasan","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Rahman","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8039-4956","authenticated-orcid":false,"given":"Matthew","family":"Czarny","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James H.","family":"Clark","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6088-0773","authenticated-orcid":false,"given":"Monica","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine","place":["Baltimore, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2017.02.015"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2014.04.014"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt099"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2002.50270.x"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00019012"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2015.10.008"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt099"},{"key":"e_1_3_1_9_2","first-page":"119","article-title":"Incidence and impact of dysphagia in patients receiving prolonged endotracheal intubation after cardiac surgery","volume":"52","author":"Barker J","year":"2009","unstructured":"Barker J, Martino R, Reichardt B, Hickey EJ, Ralph\u2010Edwards A. 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