{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T16:59:27Z","timestamp":1785257967429,"version":"3.55.0"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"14","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,7,21]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Transvenous pacemaker implantation after tricuspid valve surgery may cause adverse outcomes due to lead\u2013valve interactions. Although leadless pacemakers may mitigate these risks, empirical data remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We compared outcomes of leadless versus transvenous pacemakers following tricuspid surgery using a target trial emulation framework. We analyzed Medicare beneficiaries aged \u226565\u2009years who underwent tricuspid valve surgery and received a pacemaker during the index admission between 2017 and 2021, using propensity score matching weight analysis to control for confounders. Primary outcomes were in\u2010hospital death and 2\u2010year heart failure hospitalization. Secondary outcomes included 2\u2010year death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">We included 185 and 1336 patients in the leadless and transvenous groups, respectively. Use of leadless pacemakers increased from 6.3% in 2017 to 17.5% in 2021. Leadless pacemaker recipients more often underwent tricuspid valve replacement (29.2% versus 8.5%) while concomitant mitral surgery was less common (69.2% versus 86.8%). After adjustment, we found no evidence that in\u2010hospital death (adjusted odds ratio, 1.82 [95% CI, 0.65\u20135.13] for leadless) and 2\u2010year heart failure hospitalizations (subdistribution hazard ratio [HR], 0.88 [95% CI, 0.60\u20131.30] for leadless) differed between the 2 groups. We also found no evidence that 2\u2010year death (adjusted HR, 1.04 [95% CI, 0.69\u20131.57] for leadless) differed between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">No statistically significant differences were detected between leadless versus transvenous pacemaker implantations after tricuspid valve surgery. However, CIs were wide, and a clinically meaningful difference in either direction cannot be excluded. The study may therefore be underpowered, and the absence of echocardiographic data limits assessment of tricuspid regurgitation, warranting prospective studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.126.049636","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T03:23:25Z","timestamp":1783740205000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Outcomes of Leadless Versus Transvenous Pacemakers Following Tricuspid Valve Surgery"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5092-3127","authenticated-orcid":false,"given":"Tomonari M.","family":"Shimoda","sequence":"first","affiliation":[{"name":"Loma Linda University","place":["Loma Linda, USA"]},{"name":"University of Tsukuba","place":["Tsukuba, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2852-2946","authenticated-orcid":false,"given":"Yoshihisa","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, The University of Tokyo","place":["Tokyo, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4812-7193","authenticated-orcid":false,"given":"Hiroki A.","family":"Ueyama","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine","place":["Atlanta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3001-0966","authenticated-orcid":false,"given":"Shinobu","family":"Itagaki","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6500-7471","authenticated-orcid":false,"given":"Tsuyoshi","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine","place":["St. Louis, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-0171","authenticated-orcid":false,"given":"Hiroshi","family":"Gotanda","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Medical Center","place":["Los Angeles, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9614-8103","authenticated-orcid":false,"given":"Kosuke","family":"Inoue","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine and School of Public Health, Kyoto University","place":["Kyoto, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7898-5159","authenticated-orcid":false,"given":"Shinichi","family":"Fukuhara","sequence":"additional","affiliation":[{"name":"University of Michigan","place":["Ann Arbor, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2846-4726","authenticated-orcid":false,"given":"Gorav","family":"Ailawadi","sequence":"additional","affiliation":[{"name":"University of Michigan","place":["Ann Arbor, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7840-801X","authenticated-orcid":false,"given":"Hiroo","family":"Takayama","sequence":"additional","affiliation":[{"name":"Columbia University Irving Medical Center\/New York Presbyterian Hospital","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2487-8366","authenticated-orcid":false,"given":"Toshiki","family":"Kuno","sequence":"additional","affiliation":[{"name":"Harvard Medical School","place":["Boston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1937-4833","authenticated-orcid":false,"given":"Yusuke","family":"Tsugawa","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at UCLA","place":["Los Angeles, USA"]},{"name":"UCLA Fielding School of Public Health","place":["Los Angeles, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.09.036"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9149(98)01064-9"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2025.03.021"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2011.11.015"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.03.070"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2115961"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atssr.2024.05.022"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjon.2024.10.018"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.032760"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezu449"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.10.893"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.04.100"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2003.11.019"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2025.02.016"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab364"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000628"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2024.11.023"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac066"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-024-01796-w"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae111"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2022-071108"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2407586"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.13350"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2024.05.030"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.21037\/acs.2017.04.02"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.2621"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-4356(00)00321-8"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.124.014825"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.7501"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwaa044"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae101"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15863"},{"key":"e_1_3_1_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14870"},{"key":"e_1_3_1_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac112"},{"key":"e_1_3_1_36_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.118.007124"},{"key":"e_1_3_1_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/jce.16046"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.009530"},{"key":"e_1_3_1_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14069"},{"key":"e_1_3_1_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaf119"},{"key":"e_1_3_1_41_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-200208000-00007"},{"key":"e_1_3_1_42_2","doi-asserted-by":"publisher","DOI":"10.2147\/POR.S240913"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.126.049636","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T16:08:47Z","timestamp":1785254927000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.126.049636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,21]]},"references-count":41,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,7,21]]}},"alternative-id":["10.1161\/JAHA.126.049636"],"URL":"https:\/\/doi.org\/10.1161\/jaha.126.049636","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,21]]},"assertion":[{"value":"2026-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e049636"}}