{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:05:04Z","timestamp":1789535104240,"version":"build-2803163510"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,9,15]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Cardiac pathologies can occur after acute ischemic stroke (AIS) even in patients without prior heart disease, reflecting bidirectional brain\u2013heart interactions. We investigated sex\u2010specific differences in newly diagnosed cardiac pathologies within 1\u2009year after noncardioembolic AIS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We screened 7113 patients with a first cerebrovascular event (December 2013 to March 2021) at a tertiary stroke center and included 673 patients (39% women, aged 61.2\u2009years) with noncardioembolic AIS and no evidence of previous cardiac disease. After AIS, all patients received standard cardiologic evaluation (24\u2010hour in\u2010hospital telemetry, 24\u2010hour blood pressure monitoring, echocardiography, and 48\u2010hour Holter ECG). Electronic health records were reviewed for cardiology consultations and testing within 1\u2009year after the index event (eg, ECG, echocardiography, coronary computed tomographic angiography, cardiac magnetic resonance imaging, myocardial perfusion single\u2010photon emission computed tomography). Multivariable binary logistic regression models were adjusted for age, antihypertensive and lipid\u2010lowering therapy, hypertension, diabetes, hyperlipidemia, and smoking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Compared with women, men more frequently exhibited nonsustained ventricular tachycardia (odds ratio, 3.97 [95% CI, 1.14\u201313.86];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.031), first\u2010degree atrioventricular block (odds ratio, 5.71 [95% CI, 1.48\u201322.01];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.013), bradycardia (odds ratio, 3.40 [95% CI, 1.50\u20137.67];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.003), and polymorphic ventricular extrasystoles (odds ratio, 2.61 [95% CI, 1.43\u20134.74];\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.002) within 1\u2009year after AIS. Findings were consistent after multivariable adjustment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In this single\u2010center cohort of patients without known heart disease and noncardioembolic AIS, poststroke cardiac findings were more common in men, particularly nonsustained ventricular tachycardia and polymorphic ventricular extrasystoles. These hypothesis\u2010generating observations support further investigation into sex\u2010informed poststroke cardiac evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.126.049854","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:47:20Z","timestamp":1788965240000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Sex Differences in Cardiac Rhythm and Conduction Abnormalities After Noncardioembolic Ischemic Stroke"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4087-2121","authenticated-orcid":false,"given":"Anton","family":"Schmick","sequence":"first","affiliation":[{"name":"Clinical Neurocenter Zurich and Neuroscience Center Zurich (ZNZ)","place":["Zurich, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Heinrich","family":"Rohner","sequence":"additional","affiliation":[{"name":"University Hospital Zurich and University of Zurich","place":["Zurich, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Gebhard","sequence":"additional","affiliation":[{"name":"University Hospital Inselspital","place":["Bern, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9865-7382","authenticated-orcid":false,"given":"Andreas R.","family":"Luft","sequence":"additional","affiliation":[{"name":"University Hospital Zurich and University of Zurich","place":["Zurich, Switzerland"]},{"name":"Cereneo Center for Neurology and Rehabilitation","place":["Vitznau, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4369-7023","authenticated-orcid":false,"given":"Susanne","family":"Wegener","sequence":"additional","affiliation":[{"name":"University Hospital Zurich and University of Zurich","place":["Zurich, Switzerland"]},{"name":"Clinical Neurocenter Zurich and Neuroscience Center Zurich (ZNZ)","place":["Zurich, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70266-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.2011.2.1785"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.034131"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.15.6.990"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20806"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.03.058"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.026528"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30336-3"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.10.009"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.117.311170"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac061"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008615"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.003436"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.124.048303"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51193-0"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-021-02105-3"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.888"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-308956"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0160181"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac262"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy067"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab724.0974"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.055783"}],"container-title":["Journal 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