{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:43:24Z","timestamp":1790649804652,"version":"4.1.0"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">The clinical benefit of intravascular imaging (IVI)\u2010guided drug\u2010eluting stent implantation in patients with diabetes remains debated. The aim of this study was to compare 1\u2010year cardiac death between IVI\u2010guided and angiography\u2010guided drug\u2010eluting stent implantation in patients with diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We analyzed 11\u2009530 patients with diabetes and coronary artery disease who underwent drug\u2010eluting stent implantation from a prospective multicenter registry, stratified by IVI group (n=2425) and angiography group (n=9105). To minimize confounding, 1:1 propensity score matching was performed, resulting in 2409 matched pairs with balanced baseline clinical and angiographic characteristics. The primary end point was 1\u2010year cardiac death. Hazard ratios (HRs) with 95% CIs were estimated using Cox proportional hazards models, while Fine\u2010Gray subdistribution hazard models were used for outcomes with competing risks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      After propensity score matching, the IVI group had a greater number of implanted stents, longer total stent length, larger mean stent diameter, and larger post\u2010dilation balloon diameter (all\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.05). During 1\u2010year follow\u2010up, patients in the IVI group had a significantly lower risk of cardiac death compared with the angiography group (2.5% versus 4.3%; HR 0.59; 95% CI 0.43\u20130.80;\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001), which was confirmed by Fine\u2010Gray competing risk analysis. Moreover, IVI guidance was associated with the lower risk of 1\u2010year target lesion revascularization (3.1% versus 4.5%; HR 0.68; 95% CI 0.51\u20130.91;\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.011) and definite\/probable stent thrombosis (0.9% versus 1.6%; HR 0.56; 95% CI 0.33\u20130.96;\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      =0.036) compared with angiography guidance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In patients with diabetes and coronary artery disease, IVI\u2010guided drug\u2010eluting stent implantation revealed a significantly lower risk of 1\u2010year cardiac death than angiography guidance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.126.050709","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T11:15:33Z","timestamp":1787829333000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Intravascular Imaging\u2010Guided Drug\u2010Eluting Stent Implantation on Cardiac Death in Patients With Diabetes"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0280-8955","authenticated-orcid":false,"given":"Jing\u2010Yu","family":"Zhao","sequence":"first","affiliation":[{"name":"Nanjing First Hospital, Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0933-7406","authenticated-orcid":false,"given":"Ai\u2010Qun","family":"Chen","sequence":"additional","affiliation":[{"name":"Nanjing First Hospital, Nanjing Medical University","place":["Nanjing, 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