{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:38:14Z","timestamp":1792647494605,"version":"4.5.0"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"20","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,10,20]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p xml:lang=\"en\">Evidence linking pre\u2010 and post\u2010transcatheter aortic valve implantation (TAVI) blood pressure (BP) with cardiovascular outcomes is scarce. This study investigated the associations of pre\u2010 and post\u2010TAVI BP and their changes as a continuous variable with cardiovascular outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients undergoing TAVI at a tertiary university hospital between 2011 and 2025 with office BP available before and after TAVI were included. The primary outcome was a composite of major adverse cardiac events (MACE) at 1\u2009year. Multivariable Cox proportional hazards models incorporating restricted cubic splines for continuous variables were fitted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Among 1191 patients, BP remained relatively stable from pre\u2010TAVI to 1\u2010year follow\u2010up. Both discharge systolic BP and absolute changes therein from pre\u2010 to post\u2010TAVI were significantly associated with MACE at 1\u2009year (\n                      <jats:italic toggle=\"no\">P<\/jats:italic>\n                      &lt;0.001 for both), whereas baseline systolic BP showed no significant association. BP values &lt;115\u2009mm\u2009Hg or &gt;143\u2009mm\u2009Hg were associated with a higher risk of MACE 1\u2009year after TAVI. A decrease in systolic BP of \u22125 to \u221225\u2009mm\u2009Hg was also associated with a lower risk of MACE compared with no change.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">While BP remains generally stable in the year following TAVI, both very low and high systolic BP at discharge were associated with higher 1\u2010year MACE. Furthermore, moderate decreases in systolic BP from baseline to discharge appear to be protective. These findings highlight the potential prognostic value of BP optimization during TAVI follow\u2010up and support the role of BP measurements as a clinically translatable, independently associated with long\u2010term outcomes after TAVI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.126.050999","type":"journal-article","created":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:50:46Z","timestamp":1791633046000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Continuous Baseline and Discharge Blood Pressure on Outcomes After Transcatheter Aortic Valve Implantation"],"prefix":"10.1161","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9840-7818","authenticated-orcid":false,"given":"Thorald","family":"Stolte","sequence":"first","affiliation":[{"name":"University Hospital Basel, University of 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